Varaico: Literature-Extracted Genetic Variants

Gene:TARDBP
Variant:p.S409A
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TARDBP

NM_007375.4:p.S409A

Associated Papers

Molecular mechanisms and consequences of TDP-43 phosphorylation in neurodegeneration.

Kellett EA et al.

Molecular Neurodegeneration, 2025

Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice.

Ke YD et al.

Neuron, 2024

Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43.

Castellanos Otero P et al.

Plos One, 2024

Regulation of TDP-43 phosphorylation in aging and disease.

Eck RJ et al.

Geroscience, 2021

Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils.

Shimonaka S et al.

The Journal of Biological Chemistry, 2016

Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy.

Liachko NF et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2010

Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS.

Inukai Y et al.

Febs Letters, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."