Varaico: Literature-Extracted Genetic Variants

Gene:TARDBP
Variant:p.W412G
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TARDBP

NM_007375.4:p.W412G

Associated Papers

TDP-43 Amyloid Fibril Formation via Phase Separation-Related and -Unrelated Pathways.

Lin PH et al.

Acs Chemical Neuroscience, 2024

Decoding Missense Variants by Incorporating Phase Separation via Machine Learning.

Feng M et al.

Nature Communications, 2024

39333476 (PubMed )
Supplement: 41467_2024_52580_MOESM4_ESM.xlsx › impact_ps_mutations

The Different Faces of the TDP-43 Low-Complexity Domain: The Formation of Liquid Droplets and Amyloid Fibrils.

Chien HM et al.

International Journal of Molecular Sciences, 2021

A protein assembly mediates Xist localization and gene silencing.

Pandya-Jones A et al.

Nature, 2020

TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues.

Li HR et al.

The Journal of Biological Chemistry, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."