Associated Papers
Structural and functional characterization of human sweet taste receptor.
Shi Z et al.
Nature, 2025
Low TAS1R2 Sweet Taste Receptor Expression in Skeletal Muscle of Genetically Diverse BXD Mice Mirrors Transcriptomic Signatures of Loss-of-Function Mice.
King K et al.
Nutrients, 2025
TAS1R2/TAS1R3 Single-Nucleotide Polymorphisms Affect Sweet Taste Receptor Activation by Sweeteners: The SWEET Project.
Belloir C et al.
Nutrients, 2025
A partial loss-of-function variant (Ile191Val) of the TAS1R2 glucose receptor is associated with enhanced responses to exercise training in older adults with obesity: A translational study.
Serrano J et al.
Metabolism: Clinical and Experimental, 2025
The TAS1R2 G-protein-coupled receptor is an ambient glucose sensor in skeletal muscle that regulates NAD homeostasis and mitochondrial capacity.
Serrano J et al.
Nature Communications, 2024
Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.
Yang N et al.
Bmc Pediatrics, 2024
Somatic mutations reveal hyperactive Notch signaling and racial disparities in prurigo nodularis.
Rajeh A et al.
Medrxiv : the Preprint Server for Health Sciences, 2023
Sensitivity of human sweet taste receptor subunits T1R2 and T1R3 to activation by glucose enantiomers.
Dubovski N et al.
Chemical Senses, 2023
Associations between Sweet Taste Sensitivity and Polymorphisms (SNPs) in the TAS1R2 and TAS1R3 Genes, Gender, PROP Taster Status, and Density of Fungiform Papillae in a Genetically Homogeneous Sardinian Cohort.
Melis M et al.
Nutrients, 2022
The Ile191Val Variant of the TAS1R2 Subunit of Sweet Taste Receptors Is Associated With Reduced HbA1c in a Human Cohort With Variable Levels of Glucose Homeostasis.
Serrano J et al.
Frontiers in Nutrition, 2022
The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans.
Serrano J et al.
Molecular Metabolism, 2021
TAS1R2 rs35874116 and TRPM5 rs886277 polymorphisms are not related with risk of obesity.
Koc G et al.
International Journal of Clinical Practice, 2021
Mutation analysis of adenomas and carcinomas of the colon: Early and late drivers.
Wolff RK et al.
Genes, Chromosomes & Cancer, 2018
Single Nucleotide Polymorphisms in Taste Receptor Genes Are Associated with Snacking Patterns of Preschool-Aged Children in the Guelph Family Health Study: A Pilot Study.
Chamoun E et al.
Nutrients, 2018
Genetic Variations in Sweet Taste Receptor Gene Are Related to Chocolate Powder and Dietary Fiber Intake in Obese Children and Adolescents.
Pioltine MB et al.
Journal of Personalized Medicine, 2018
Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione.
Kürschner G et al.
Oncotarget, 2017
Genetic variations in taste perception modify alcohol drinking behavior in Koreans.
Choi JH et al.
Appetite, 2017
Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.
Maguire SL et al.
The Journal of Pathology, 2016
Sweet Taste Receptor TAS1R2 Polymorphism (Val191Val) Is Associated with a Higher Carbohydrate Intake and Hypertriglyceridemia among the Population of West Mexico.
Ramos-Lopez O et al.
Nutrients, 2016
Evaluation of Hybridization Capture Versus Amplicon-Based Methods for Whole-Exome Sequencing.
Samorodnitsky E et al.
Human Mutation, 2015
Multiple loss-of-function variants of taste receptors in modern humans.
Fujikura K
Scientific Reports, 2015
Association of sweet taste receptor gene polymorphisms with dental caries experience in school children.
Haznedaroğlu E et al.
Caries Research, 2015
GLUT2 and TAS1R2 Polymorphisms and Susceptibility to Dental Caries.
Izakovicova Holla L et al.
Caries Research, 2015
Variation in the TAS1R2 Gene, Sweet Taste Perception and Intake of Sugars.
Dias AG et al.
Journal of Nutrigenetics and Nutrigenomics, 2015
Association of GLUT2 and TAS1R2 genotypes with risk for dental caries.
Kulkarni GV et al.
Caries Research, 2013
The association of bovine T1R family of receptors polymorphisms with cattle growth traits.
Zhang CL et al.
Research in Veterinary Science, 2012
Genetic variation in TAS1R2 (Ile191Val) is associated with consumption of sugars in overweight and obese individuals in 2 distinct populations.
Eny KM et al.
The American Journal of Clinical Nutrition, 2010
Evaluation of the association between the TAS1R2 and TAS1R3 variants and food intake and nutritional status in children.
Melo SV et al.
Genetics and Molecular Biology, 0