Associated Papers
TBC1D1 functions as a negative regulator of satellite cells for muscle regeneration.
Yang X et al.
Nature Communications, 2025
The Rab GTPase in the heart: Pivotal roles in development and disease.
Liu J et al.
Life Sciences, 2022
Illumination of the Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle.
Larsen JK et al.
Diabetes, 2022
Rab2A regulates the progression of nonalcoholic fatty liver disease downstream of AMPK-TBC1D1 axis by stabilizing PPARγ.
Chen ZY et al.
Plos Biology, 2022
The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy.
Tona R et al.
Human Molecular Genetics, 2019
AKT and AMP-activated protein kinase regulate TBC1D1 through phosphorylation and its interaction with the cytosolic tail of insulin-regulated aminopeptidase IRAP.
Mafakheri S et al.
The Journal of Biological Chemistry, 2018
Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity.
Thomas EC et al.
The Biochemical Journal, 2018
Tbc1d1 deletion suppresses obesity in leptin-deficient mice.
Dokas J et al.
International Journal of Obesity (2005), 2016
Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing.
Volckmar AL et al.
Plos One, 2016
Deletion of the Rab GAP Tbc1d1 modifies glucose, lipid, and energy homeostasis in mice.
Hargett SR et al.
American Journal of Physiology. Endocrinology and Metabolism, 2015
GWAS-identified common variants for obesity are not associated with the risk of developing colorectal cancer.
Sainz J et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2014
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
Stribl C et al.
The Journal of Biological Chemistry, 2014
Genetic modifiers of cardiorespiratory fitness response to lifestyle intervention.
Peter I et al.
Medicine and Science in Sports and Exercise, 2014
Identification and Association of SNPs in TBC1D1 Gene with Growth Traits in Two Rabbit Breeds.
Yang ZJ et al.
Asian-australasian Journal of Animal Sciences, 2013
Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle.
Dokas J et al.
Endocrinology, 2013
Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle.
Middelbeek RJ et al.
Nutrition & Diabetes, 2013
Exploratory study on association of genetic variation in TBC1D1 with antipsychotic-induced weight gain.
Brandl EJ et al.
Human Psychopharmacology, 2013
The TBC1D1 gene: structure, function, and association with obesity and related traits.
Fontanesi L et al.
Vitamins and Hormones, 2013
Structural and population-based evaluations of TBC1D1 p.Arg125Trp.
Richardson TG et al.
Plos One, 2013
The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism.
Szekeres F et al.
American Journal of Physiology. Endocrinology and Metabolism, 2012
Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle.
Lau P et al.
Diabetologia, 2011
The porcine TBC1D1 gene: mapping, SNP identification, and association study with meat, carcass and production traits in Italian heavy pigs.
Fontanesi L et al.
Molecular Biology Reports, 2011
TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.
An D et al.
Diabetes, 2010
Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity.
Chadt A et al.
Nature Genetics, 2008
R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population.
Meyre D et al.
Human Molecular Genetics, 2008
Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1.
Roach WG et al.
The Biochemical Journal, 2007
TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition.
Stone S et al.
Human Molecular Genetics, 2006