Varaico: Literature-Extracted Genetic Variants

Gene:TBC1D9
Variant:p.Q487*
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TBC1D9

NM_015130.3:p.Q487*

Associated Papers

Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani Population.

Afsar NA et al.

Scientific Reports, 2019

Drug-related genetic polymorphisms affecting severe chemotherapy-induced neutropenia in breast cancer patients: A hospital-based observational study.

Tsuji D et al.

Medicine, 2016

Haplotype structure and allele frequencies of CYP2B6 in Spaniards and Central Americans.

Arenaz I et al.

Fundamental & Clinical Pharmacology, 2010

Association of drug metabolism gene polymorphisms with toxicities, graft-versus-host disease and survival after HLA-identical sibling hematopoietic stem cell transplantation for patients with leukemia.

Rocha V et al.

Leukemia, 2009

Efavirenz induces CYP2B6-mediated hydroxylation of bupropion in healthy subjects.

Robertson SM et al.

Journal of Acquired Immune Deficiency Syndromes (1999), 2008

Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines.

Brandon EF et al.

Toxicology and Applied Pharmacology, 2006

Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens.

Tsuchiya K et al.

Biochemical and Biophysical Research Communications, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."