Varaico: Literature-Extracted Genetic Variants

Gene:TBK1
Variant:p.K30R
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TBK1

NM_013254.4:p.K30R

Associated Papers

TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery.

Saha B et al.

Cell Reports, 2024

Factor inhibiting HIF negatively regulates antiviral innate immunity via hydroxylation of IKKϵ.

Cai X et al.

Cell Reports, 2024

TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery.

Saha B et al.

Biorxiv : the Preprint Server for Biology, 2023

E3 ubiquitin ligase RNF128 promotes innate antiviral immunity through K63-linked ubiquitination of TBK1.

Song G et al.

Nature Immunology, 2016

The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing.

Pourcelot M et al.

Bmc Biology, 2016

Structure and ubiquitination-dependent activation of TANK-binding kinase 1.

Tu D et al.

Cell Reports, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."