Associated Papers
Functional consequences of TCF4 missense substitutions associated with Pitt-Hopkins syndrome, mild intellectual disability, and schizophrenia.
Sirp A et al.
The Journal of Biological Chemistry, 2021
Survival control of oligodendrocyte progenitor cells requires the transcription factor 4 during olfactory bulb development.
Zhang Y et al.
Cell Death & Disease, 2021
The subcellular localization of bHLH transcription factor TCF4 is mediated by multiple nuclear localization and nuclear export signals.
Greb-Markiewicz B et al.
Scientific Reports, 2019
Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.
Yang J et al.
Nucleic Acids Research, 2019
Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities.
Li H et al.
Molecular Psychiatry, 2019
Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma.
Jain N et al.
Science Translational Medicine, 2019
The schizophrenia- and autism-associated gene, transcription factor 4 regulates the columnar distribution of layer 2/3 prefrontal pyramidal neurons in an activity-dependent manner.
Page SC et al.
Molecular Psychiatry, 2018
Common Pathophysiology in Multiple Mouse Models of Pitt-Hopkins Syndrome.
Thaxton C et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2018
Introducing Pitt-Hopkins syndrome-associated mutations of TCF4 to Drosophila daughterless.
Tamberg L et al.
Biology Open, 2015
Pitt-Hopkins syndrome-associated mutations in TCF4 lead to variable impairment of the transcription factor function ranging from hypomorphic to dominant-negative effects.
Sepp M et al.
Human Molecular Genetics, 2012
Novel comprehensive diagnostic strategy in Pitt-Hopkins syndrome: clinical score and further delineation of the TCF4 mutational spectrum.
Whalen S et al.
Human Mutation, 2012
Two percent of patients suspected of having Angelman syndrome have TCF4 mutations.
Takano K et al.
Clinical Genetics, 2010
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