Associated Papers
Phenotypical mapping of TP53 unique missense mutations spectrum in human cancers.
Malhotra L et al.
Journal of Biomolecular Structure & Dynamics, 2025
p53 in colorectal cancer: from a master player to a privileged therapy target.
Yan S et al.
Journal of Translational Medicine, 2025
Complete Models of p53 Better Inform the Impact of Hotspot Mutations.
Solares MJ et al.
International Journal of Molecular Sciences, 2022
p53 amyloid aggregation in cancer: function, mechanism, and therapy.
Li J et al.
Experimental Hematology & Oncology, 2022
Potential of rescue and reactivation of tumor suppressor p53 for cancer therapy.
Hibino E et al.
Biophysical Reviews, 2022
Semi-Synthesis of Small Molecules of Aminocarbazoles: Tumor Growth Inhibition and Potential Impact on p53.
Long S et al.
Molecules (basel, Switzerland), 2021
Association of MicroRNA-21 with p53 at Mutant Sites R175H and R248Q, Clinicopathological Features, and Prognosis of NSCLC.
Zhou Y et al.
Molecular Therapy Oncolytics, 2020
Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib.
Wang Z et al.
Molecular Cancer Research : Mcr, 2020
Hsp70- and Hsp90-Mediated Regulation of the Conformation of p53 DNA Binding Domain and p53 Cancer Variants.
Boysen M et al.
Molecular Cell, 2019
Hot Spot Mutation in TP53 (R248Q) Causes Oncogenic Gain-of-Function Phenotypes in a Breast Cancer Cell Line Derived from an African American patient.
Shtraizent N et al.
International Journal of Environmental Research and Public Health, 2015
APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells.
Mohell N et al.
Cell Death & Disease, 2015
Molecular profiling of infiltrating urothelial carcinoma of bladder and nonbladder origin.
Millis SZ et al.
Clinical Genitourinary Cancer, 2015
TP53 mutants in the tower of babel of cancer progression.
Bisio A et al.
Human Mutation, 2014
Ensemble-based computational approach discriminates functional activity of p53 cancer and rescue mutants.
Demir Ö et al.
Plos Computational Biology, 2011
Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors.
Levy CB et al.
The International Journal of Biochemistry & Cell Biology, 2011
Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers.
Dearth LR et al.
Carcinogenesis, 2007
p53 Gene mutations in sporadic colorectal carcinoma in Guangxi region.
Gao F et al.
Cancer Investigation, 2006
Harmonized microarray/mutation scanning analysis of TP53 mutations in undissected colorectal tumors.
Favis R et al.
Human Mutation, 2004
p53 mutations and expression in breast carcinoma in situ.
Lukas J et al.
The American Journal of Pathology, 2000
WAF1/Cip1 gene polymorphism and expression in carcinomas of the breast, ovary, and endometrium.
Lukas J et al.
The American Journal of Pathology, 1997