Associated Papers
Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus.
Rashid I et al.
The Journal of Biological Chemistry, 2021
Reactive oxygen species stress increases accumulation of tyrosyl-DNA phsosphodiesterase 1 within mitochondria.
Fam HK et al.
Scientific Reports, 2018
TDP1 is required for efficient non-homologous end joining in human cells.
Li J et al.
Dna Repair, 2017
Association of tyrosyl-DNA phosphodiesterase 1 polymorphism with Tourette syndrome in Taiwanese patients.
Wu BT et al.
Journal of Clinical Laboratory Analysis, 2013
TDP1 serine 81 promotes interaction with DNA ligase IIIalpha and facilitates cell survival following DNA damage.
Chiang SC et al.
Cell Cycle (georgetown, Tex.), 2010
Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK.
Das BB et al.
The Embo Journal, 2009
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