Varaico: Literature-Extracted Genetic Variants

Gene:TEAD1
Variant:p.Y421H
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TEAD1

NM_021961.6:p.Y421H

Associated Papers

Novel TEAD1 gene variant in a Serbian family with Sveinsson's chorioretinal atrophy.

Grubisa I et al.

Experimental Eye Research, 2021

The Hippo Tumor Suppressor Pathway (YAP/TAZ/TEAD/MST/LATS) and EGFR-RAS-RAF-MEK in cancer metastasis.

Zinatizadeh MR et al.

Genes & Diseases, 2021

The Hippo Signaling Pathway in Development and Disease.

Zheng Y et al.

Developmental Cell, 2019

Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy.

Bokhovchuk F et al.

The Febs Journal, 2019

Regulation of the Hippo Pathway Transcription Factor TEAD.

Lin KC et al.

Trends in Biochemical Sciences, 2017

Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex.

Kaan HYK et al.

Scientific Reports, 2017

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.

Komor AC et al.

Nature, 2016

27096365 (PubMed )
Supplement: NIHMS774092-supplement-1.pdf

A De Novo Mutation in TEAD1 Causes Non-X-Linked Aicardi Syndrome.

Schrauwen I et al.

Investigative Ophthalmology & Visual Science, 2015

Regulation of the Hippo pathway and implications for anticancer drug development.

Park HW et al.

Trends in Pharmacological Sciences, 2013

Structures of YAP protein domains reveal promising targets for development of new cancer drugs.

Sudol M et al.

Seminars in Cell & Developmental Biology, 2012

Alteration of TEAD1 expression levels confers apoptotic resistance through the transcriptional up-regulation of Livin.

Landin Malt A et al.

Plos One, 2012

PhenoHM: human-mouse comparative phenome-genome server.

Sardana D et al.

Nucleic Acids Research, 2010

20507906 (PubMed )
Supplement: gkq472_nar-00429-web-b-2010-File006.xls › MPO_to_OMIM_allelic_Variants

Structural basis of YAP recognition by TEAD4 in the hippo pathway.

Chen L et al.

Genes & Development, 2010

Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium.

Tosi J et al.

Ophthalmology, 2009

A Sveinsson's chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ.

Kitagawa M

Biochemical and Biophysical Research Communications, 2007

A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration).

Fossdal R et al.

Human Molecular Genetics, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."