Varaico: Literature-Extracted Genetic Variants

Gene:TEAD4
Variant:p.Y429H
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TEAD4

NM_003213.4:p.Y429H

Associated Papers

The tumor suppressor NF2 modulates TEAD4 stability and activity in Hippo signaling via direct interaction.

Wu M et al.

The Journal of Biological Chemistry, 2024

38522513 (PubMed )
Supplement: mmc1.docx

TEAD4 is a master regulator of high-risk nasopharyngeal carcinoma.

Wang YQ et al.

Science Advances, 2023

ROCK1 mechano-signaling dependency of human malignancies driven by TEAD/YAP activation.

Esposito D et al.

Nature Communications, 2022

Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy.

Bokhovchuk F et al.

The Febs Journal, 2019

Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component mutations.

Troilo A et al.

Oncotarget, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."