Varaico: Literature-Extracted Genetic Variants

Gene:TERT
Variant:p.L77L
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TERT

NM_198253.3:p.L77L

Associated Papers

The C250T Mutation of TERTp Might Grant a Better Prognosis to Glioblastoma by Exerting Less Biological Effect on Telomeres and Chromosomes Than the C228T Mutation.

Gorria T et al.

Cancers, 2024

TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entities.

Kuhn CK et al.

Plos One, 2023

37418389 (PubMed )
Supplement: pone.0281487.s006.xlsx › 5D_TERT_pm_subtypes

Establishment and Validation of the Detection of TERT Promoter Mutations by Human Gliomas U251 Cell Lines.

Bai H et al.

Biomed Research International, 2021

Co-Occurrence of Hotspot Point Mutation and Novel Deletion Mutation of TERT Promoter in Solid Variant Papillary Thyroid Carcinoma in a Patient with Synchronous Esophageal Cancer.

Han J et al.

Diagnostics (basel, Switzerland), 2020

Impact of BRAF V600E and TERT Promoter Mutations on Response to Therapy in Papillary Thyroid Cancer.

Trybek T et al.

Endocrinology, 2019

TERT promoter hotspot mutations in breast cancer.

Shimoi T et al.

Breast Cancer (tokyo, Japan), 2018

TERT promoter mutations and their correlation with BRAF and RAS mutations in a consecutive cohort of 145 thyroid cancer cases.

Insilla AC et al.

Oncology Letters, 2018

Regulation of mutant TERT by BRAF V600E/MAP kinase pathway through FOS/GABP in human cancer.

Liu R et al.

Nature Communications, 2018

29422527 (PubMed )
Supplement: 41467_2018_3033_MOESM1_ESM.pdf

Identification of cis-regulatory mutations generating de novo edges in personalized cancer gene regulatory networks.

Kalender Atak Z et al.

Genome Medicine, 2017

TERT promoter mutations are rare in bone and soft tissue sarcomas of Japanese patients.

Saito T et al.

Molecular and Clinical Oncology, 2016

Coexistence of TERT promoter and BRAF mutations in cutaneous melanoma is associated with more clinicopathological features of aggressiveness.

Macerola E et al.

Virchows Archiv : an International Journal of Pathology, 2015

TERT promoter mutations are associated with distant metastases in papillary thyroid carcinoma.

Gandolfi G et al.

European Journal of Endocrinology, 2015

Absence of TERT promoter mutations in esophageal adenocarcinoma.

van Nistelrooij AM et al.

International Journal of Cancer, 2014

Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome.

Allory Y et al.

European Urology, 2014

Highly recurrent TERT promoter mutations in human melanoma.

Huang FW et al.

Science (new York, N.y.), 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."