Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.D1242V
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TET2

NM_001127208.3:p.D1242V

Associated Papers

The cysteine-rich domain of TET2 binds preferentially to mono- and dimethylated histone H3K36.

Yamagata K et al.

Journal of Biochemistry, 2017

Profound parental bias associated with chromosome 14 acquired uniparental disomy indicates targeting of an imprinted locus.

Chase A et al.

Leukemia, 2015

The TET2 interactors and their links to hematological malignancies.

Pan F et al.

Iubmb Life, 2015

WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation.

Wang Y et al.

Molecular Cell, 2015

Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Gnad F et al.

Bmc Genomics, 2013

23819521 (PubMed )
Supplement: 1471-2164-14-S3-S7-S1.xlsx › COSMIC

Feature-based classification of amino acid substitutions outside conserved functional protein domains.

Gemovic B et al.

Thescientificworldjournal, 2013

24348198 (PubMed )
Supplement: 948617.f1.pdf

Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm.

Beer PA et al.

Blood, 2010

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.

Abdel-Wahab O et al.

Blood, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."