Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.D1384A
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TET2

NM_001127208.3:p.D1384A

Associated Papers

The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation.

Yeaton A et al.

Cancer Discovery, 2022

TET2-BCLAF1 transcription repression complex epigenetically regulates the expression of colorectal cancer gene Ascl2 via methylation of its promoter.

Shang Y et al.

The Journal of Biological Chemistry, 2022

TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis.

Mahfoudhi E et al.

Dna Repair, 2016

Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence.

Li C et al.

Cell Reports, 2015

AF9 promotes hESC neural differentiation through recruiting TET2 to neurodevelopmental gene loci for methylcytosine hydroxylation.

Qiao Y et al.

Cell Discovery, 2015

TET2 promotes histone O-GlcNAcylation during gene transcription.

Chen Q et al.

Nature, 2013

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.

Ko M et al.

Nature, 2010

21057493 (PubMed )
Supplement: NIHMS247005-supplement-3.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."