Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.H1881Q
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TET2

NM_001127208.3:p.H1881Q

Associated Papers

Identification of t(X;1)(q28;q21) generating a novel GATAD2B::MTCP1 gene fusion in CMML and its persistence during progression to AML.

Liu YZ et al.

Hematology (amsterdam, Netherlands), 2025

Human HDAC6 senses valine abundancy to regulate DNA damage.

Jin J et al.

Nature, 2025

TET2 Suppresses VHL Deficiency-Driven Clear Cell Renal Cell Carcinoma by Inhibiting HIF Signaling.

Zhang X et al.

Cancer Research, 2022

Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells.

Pastoret C et al.

Blood, 2021

Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation.

Chang YI et al.

British Journal of Haematology, 2014

Clinical and biological impact of TET2 mutations and expression in younger adult AML patients treated within the EORTC/GIMEMA AML-12 clinical trial.

Aslanyan MG et al.

Annals of Hematology, 2014

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.

Ko M et al.

Nature, 2010

21057493 (PubMed )
Supplement: NIHMS247005-supplement-3.pdf

Acquired mutations in TET2 are common in myelodysplastic syndromes.

Langemeijer SM et al.

Nature Genetics, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."