Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.R1896M
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TET2

NM_001127208.3:p.R1896M

Associated Papers

TET2 missense variants in human neoplasia. A proposal of structural and functional classification.

Bussaglia E et al.

Molecular Genetics & Genomic Medicine, 2019

Genomic Comparison of Endometrioid Endometrial Carcinoma and Its Precancerous Lesions in Chinese Patients by High-Depth Next Generation Sequencing.

Wang Y et al.

Frontiers in Oncology, 2019

30886832 (PubMed )
Supplement: Table_2.xls › Table_2

Convenient expression, purification and quantitative liquid chromatography-tandem mass spectrometry-based analysis of TET2 5-methylcytosine demethylase.

Jaiswal M et al.

Protein Expression and Purification, 2017

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.

Laukka T et al.

The Journal of Biological Chemistry, 2016

Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles.

Hatlen MA et al.

The Journal of Experimental Medicine, 2016

26666262 (PubMed )
Supplement: supp_jem.20150524_JEM_20150524_sm.pdf

Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation.

Hu L et al.

Cell, 2013

Feature-based classification of amino acid substitutions outside conserved functional protein domains.

Gemovic B et al.

Thescientificworldjournal, 2013

24348198 (PubMed )
Supplement: 948617.f1.pdf

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.

Ko M et al.

Nature, 2010

Mutation in TET2 in myeloid cancers.

Delhommeau F et al.

The New England Journal of Medicine, 2009

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