Varaico: Literature-Extracted Genetic Variants

Gene:TFE3
Variant:p.S321A
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TFE3

NM_006521.6:p.S321A

Associated Papers

Regulation of Caenorhabditis elegans HLH-30 subcellular localization dynamics: Evidence for a redox-dependent mechanism.

Colino-Lage H et al.

Free Radical Biology & Medicine, 2024

A central role for regulated protein stability in the control of TFE3 and MITF by nutrients.

Nardone C et al.

Molecular Cell, 2023

A conserved cysteine-based redox mechanism sustains TFEB/HLH-30 activity under persistent stress.

Martina JA et al.

The Embo Journal, 2021

CDK4/6 regulate lysosome biogenesis through TFEB/TFE3.

Yin Q et al.

The Journal of Cell Biology, 2020

32662822 (PubMed )
Supplement: JCB_201911036_TableS5.xlsx › Sheet1

The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage.

Brady OA et al.

Elife, 2018

TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes.

Willett R et al.

Nature Communications, 2017

The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris.

Martina JA et al.

Science Signaling, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."