Associated Papers
The ATAC complex represses the transcriptional program of the autophagy-lysosome pathway via its E3 ubiquitin ligase activity.
Wang X et al.
Cell Reports, 2024
USP7 protects TFEB from proteasome-mediated degradation.
Keshri S et al.
Cell Reports, 2024
The regulatory mechanism and therapeutic potential of transcription factor EB in neurodegenerative diseases.
Jiao F et al.
Cns Neuroscience & Therapeutics, 2023
Sirtuins in Alzheimer's Disease: SIRT2-Related GenoPhenotypes and Implications for PharmacoEpiGenetics.
Cacabelos R et al.
International Journal of Molecular Sciences, 2019
Importance of TFEB acetylation in control of its transcriptional activity and lysosomal function in response to histone deacetylase inhibitors.
Zhang J et al.
Autophagy, 2018
Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia.
Bao J et al.
Protein & Cell, 2016
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