Varaico: Literature-Extracted Genetic Variants

Gene:TFRC
Variant:p.Y20C
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TFRC

NM_001128148.3:p.Y20C

Associated Papers

An internalization motif is created in the cytoplasmic domain of the transferrin receptor by substitution of a tyrosine at the first position of a predicted tight turn.

Pytowski B et al.

The Journal of Biological Chemistry, 1995

YTRF is the conserved internalization signal of the transferrin receptor, and a second YTRF signal at position 31-34 enhances endocytosis.

Collawn JF et al.

The Journal of Biological Chemistry, 1993

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."