Varaico: Literature-Extracted Genetic Variants

Gene:TG
Variant:p.A53T
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TG

NM_003235.5:p.A53T

Associated Papers

Distinct profiles of LRRK2 activation and Rab GTPase phosphorylation in clinical samples from different PD cohorts.

Petropoulou-Vathi L et al.

Npj Parkinson's Disease, 2022

Targeting of Lysosomal Pathway Genes for Parkinson's Disease Modification: Insights From Cellular and Animal Models.

Abe T et al.

Frontiers in Neurology, 2021

Structures and free energy landscapes of the A53T mutant-type α-synuclein protein and impact of A53T mutation on the structures of the wild-type α-synuclein protein with dynamics.

Coskuner O et al.

Acs Chemical Neuroscience, 2013

Novel suppressors of alpha-synuclein toxicity identified using yeast.

Liang J et al.

Human Molecular Genetics, 2008

PA700, the regulatory complex of the 26S proteasome, interferes with alpha-synuclein assembly.

Ghee M et al.

The Febs Journal, 2005

Alpha-synuclein targets the plasma membrane via the secretory pathway and induces toxicity in yeast.

Dixon C et al.

Genetics, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."