Varaico: Literature-Extracted Genetic Variants

Gene:TGFB1
Variant:p.R25P
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TGFB1

NM_000660.7:p.R25P

Associated Papers

Suggestive Contribution of Sequence Signal Gene Variants of TGF-β1 in Development of Type 1 Diabetes, Diabetic Neuropathy, and Modulation of Lipid Profile.

Mihoubi E et al.

Biochemical Genetics, 2025

Pharmacogenomic landscape of TNF inhibitors in the Middle Eastern Qatari population.

Jan Z et al.

Frontiers in Immunology, 2025

41346622 (PubMed )
Supplement: Table2.xlsx › Supplementary_Table_8

Genetic Polymorphisms of COL1A1 Promoter Region (rs1800012) and TGFB1 Signal Peptide (rs1800471): Role in Cervical Insufficiency Susceptibility?

Gulucu S et al.

Reproductive Sciences (thousand Oaks, Calif.), 2024

Genetic Factors Contributing to the Pathogenesis of Essential Hypertension in Two African Populations.

Kalideen K et al.

Journal of Personalized Medicine, 2024

38541065 (PubMed )
Supplement: jpm-14-00323-s001.zip › jpm-2900250-supplementary.pdf

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.

Yu H et al.

Elife, 2024

38277211 (PubMed )
Supplement: elife-89762-supp1.xlsx › Variants

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.

Yu H et al.

Biorxiv : the Preprint Server for Biology, 2023

37292598 (PubMed )
Supplement: media-1.xlsx › Variants

Comparative analysis of histopathological parameters, genome-wide copy number alterations, and variants in genes involved in cell cycle regulation in chordomas of the skull base and sacrum.

Salle H et al.

Journal of Neuropathology and Experimental Neurology, 2023

The rs1800469 T/T and rs1800470 C/C genotypes of the TGFB1 gene confer protection against diabetic retinopathy in a Southern Brazilian population.

Costa AR et al.

Genetics and Molecular Biology, 2023

The Impact of Genetic Variability of TGF-Beta Signaling Biomarkers in Major Craniofacial Syndromes.

Yapijakis C et al.

Advances in Experimental Medicine and Biology, 2023

Genetic susceptibility of bladder cancer in the Lebanese population.

Kourie HR et al.

Bmc Medical Genomics, 2022

36253817 (PubMed )
Supplement: 12920_2022_1372_MOESM1_ESM.xlsx › sheet_1

Case-Control Genotyping of the c.788C>T Variant of Transforming Growth Factor-Beta 1 Gene in Otosclerosis in the South Indian Population.

Kale D et al.

The Journal of International Advanced Otology, 2022

Genetic dominance of transforming growth factor-β1 polymorphisms in chronic liver disease.

Cai X et al.

Frontiers in Immunology, 2022

TGF-Β1 & PNPLA3 Genetic Variants and the Risk of Hepatic Fibrosis and HCC in Egyptian Patients with HCV-Related Liver Cirrhosis.

Nomair AM et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2021

The association of transforming growth factor beta 1 gene polymorphisms with arthritis: a systematic review and meta-analysis.

Liu S et al.

Clinical and Experimental Medicine, 2021

Association between idiopathic recurrent pregnancy loss and genetic polymorphisms in cytokine and matrix metalloproteinase genes.

Wysocka U et al.

Ginekologia Polska, 2021

Genetic Polymorphisms of the TGFB1 Signal Peptide and Promoter Region: Role in Wilms Tumor Susceptibility?

Ishibashi CM et al.

Journal of Kidney Cancer and Vhl, 2021

Association between gene polymorphisms of TGF-β and Smad3 and susceptibility to arthritis: a meta-analysis.

Liu J et al.

Expert Review of Clinical Immunology, 2020

Transforming growth factor beta 1 (TGFβ1) polymorphisms and unexplained infertility: A genetic association study.

Marhemati F et al.

Systems Biology in Reproductive Medicine, 2020

Transforming growth factor beta 1 (TGFβ1) plasmatic levels in breast cancer and neoplasia-free women: Association with patients' characteristics and TGFB1 haplotypes.

Vitiello GAF et al.

Cytokine, 2020

Genetic Variants Detected Using Cell-Free DNA from Blood and Tumor Samples in Patients with Inflammatory Breast Cancer.

Winn JS et al.

International Journal of Molecular Sciences, 2020

32075053 (PubMed )
Supplement: ijms-21-01290-s001.zip › ijms-703397_SI › Supplementary_Table_3.xlsx › Supplementary_Table_2_final

Investigation of TGFB1 -1347C>T variant as a biomarker after allogeneic hematopoietic stem cell transplantation.

Kövy P et al.

Bone Marrow Transplantation, 2020

A link between promoter polymorphisms of the transforming growth factor β1 (TGFB1) and TGF-β1 receptor II (TGFBR2) genes and relapsing-remitting multiple sclerosis.

Grigorova A et al.

Folia Neuropathologica, 2020

Transforming growth factor beta 1 polymorphisms and haplotypes associated with breast cancer susceptibility: A case-control study in Tunisian women.

Hadj-Ahmed M et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2019

MicroRNA-655-3p and microRNA-497-5p inhibit cell proliferation in cultured human lip cells through the regulation of genes related to human cleft lip.

Gajera M et al.

Bmc Medical Genomics, 2019

31122291 (PubMed )
Supplement: 12920_2019_535_MOESM1_ESM.zip › 3_Human_Cleft_Lip__Table_S3__Significant_R2.xlsx › Single_Gene_Significant

Whole-exome sequencing in multiplex preeclampsia families identifies novel candidate susceptibility genes.

Melton PE et al.

Journal of Hypertension, 2019

Transforming growth factor beta 1 (TGFβ1) polymorphisms and haplotype structures have dual roles in breast cancer pathogenesis.

Vitiello GAF et al.

Journal of Cancer Research and Clinical Oncology, 2018

Genetic and epigenetic variations associated with idiopathic recurrent pregnancy loss.

Arias-Sosa LA et al.

Journal of Assisted Reproduction and Genetics, 2018

The Association between TGF-β1 G915C (Arg25Pro) Polymorphism and the Development of Primary Open Angle Glaucoma: A Case-Control Study.

Karmiris E et al.

Medical Hypothesis, Discovery & Innovation Ophthalmology Journal, 2018

Transmission analysis of TGFB1 gene polymorphisms in non-syndromic cleft lip with or without cleft palate.

Raju GT et al.

International Journal of Pediatric Otorhinolaryngology, 2017

The profile of selected single nucleotide polymorphisms in patients with hypertension and heart failure with preserved and mid-range ejection fraction.

Bielecka-Dabrowa A et al.

Scientific Reports, 2017

Increased Serum Levels of IL-28 and IL-29 and the Protective Effect of IL28B rs8099917 Polymorphism in Patients with Hashimoto's Thyroiditis.

Arpaci D et al.

Immunological Investigations, 2016

Pro-inflammatory cytokines and their epistatic interactions in genetic susceptibility to schizophrenia.

Srinivas L et al.

Journal of Neuroinflammation, 2016

Association Between the Transforming Growth Factor Beta 1 Gene Polymorphisms and Turkish Patients with Nonsyndromic Cleft Lip With/Without Cleft Palate.

Oner DA et al.

Genetic Testing and Molecular Biomarkers, 2016

The African-387 C>T TGFB1 variant is functional and associates with the ophthalmoplegic complication in juvenile myasthenia gravis.

Nel M et al.

Journal of Human Genetics, 2016

Polymorphism in TGFB1 is associated with worse non-relapse mortality and overall survival after stem cell transplantation with unrelated donors.

Arrieta-Bolaños E et al.

Haematologica, 2016

Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas.

Montazeri Z et al.

International Journal of Epidemiology, 2016

Altered erythrocyte membrane protein composition mirrors pleiotropic effects of hypertension susceptibility genes and disease pathogenesis.

Polonikov AV et al.

Journal of Hypertension, 2015

Genetic analysis of nonalcoholic fatty liver disease within a Caribbean-Hispanic population.

Edelman D et al.

Molecular Genetics & Genomic Medicine, 2015

c.29C>T polymorphism in the transforming growth factor-β1 (TGFB1) gene correlates with increased risk of urinary bladder cancer.

Gautam KA et al.

Cytokine, 2015

Transforming growth factor beta-1 (TGF-β1) gene single nucleotide polymorphisms (SNPs) and susceptibility to pre-eclampsia in Iranian women: A case-control study.

Khani M et al.

Pregnancy Hypertension, 2015

Pathogenesis of intracranial aneurysm is mediated by proinflammatory cytokine TNFA and IFNG and through stochastic regulation of IL10 and TGFB1 by comorbid factors.

Sathyan S et al.

Journal of Neuroinflammation, 2015

Novel alleles of the transforming growth factor β-1 regulatory region and exon 1.

Arrieta-Bolaños E et al.

Tissue Antigens, 2015

Germ line polymorphisms as predictive markers for pre-surgical radiochemotherapy in locally advanced rectal cancer: a 5-year literature update and critical review.

Pezzolo E et al.

European Journal of Clinical Pharmacology, 2015

Assessment of the frequency of the transforming growth factor beta-1 sequence polymorphisms in patients with alcohol dependence syndrome.

Augustyńska B et al.

Acta Biochimica Polonica, 2015

Sex differences in TGFB-β signaling with respect to age of onset and cognitive functioning in schizophrenia.

Frydecka D et al.

Neuropsychiatric Disease and Treatment, 2015

Genetics of Interstitial Lung Disease: Vol de Nuit (Night Flight).

Furukawa H et al.

Clinical Medicine Insights. Circulatory, Respiratory and Pulmonary Medicine, 2015

Association of a Large Panel of Cytokine Gene Polymorphisms with Complications and Comorbidities in Type 2 Diabetes Patients.

Rodrigues KF et al.

Journal of Diabetes Research, 2015

Variants of the Coagulation and Inflammation Genes Are Replicably Associated with Myocardial Infarction and Epistatically Interact in Russians.

Barsova RM et al.

Plos One, 2015

26658659 (PubMed )
Supplement: pone.0144190.s002.doc
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."