Associated Papers
Harnessing iPSCs, 3D organoids, and multiomics to model rare vascular diseases: Emerging new approach methodologies.
Liu L et al.
Vascular Medicine (london, England), 2026
Engineered vascular grafts lend unique insight to pathophysiology of aortic aneurysms.
Naegeli KM et al.
Cell Stem Cell, 2024
Bioengineered vascular grafts with a pathogenic TGFBR1 variant model aneurysm formation in vivo and reveal underlying collagen defects.
Yang Y et al.
Science Translational Medicine, 2024
Understanding genomic medicine for thoracic aortic disease through the lens of induced pluripotent stem cells.
Singh AA et al.
Frontiers in Cardiovascular Medicine, 2024
The endometrial cancer A230V-ALK5 (TGFBR1) mutant attenuates TGF-β signaling and exhibits reduced in vitro sensitivity to ALK5 inhibitors.
Yu EJ et al.
Plos One, 2024
hiPSC Modeling of Lineage-Specific Smooth Muscle Cell Defects Caused by TGFBR1A230T Variant, and Its Therapeutic Implications for Loeys-Dietz Syndrome.
Zhou D et al.
Circulation, 2021
Variant discovery in patients with Mendelian vascular anomalies by next-generation sequencing and their use in patient clinical management.
Mattassi R et al.
Journal of Vascular Surgery, 2018
Novel inactivating mutations of transforming growth factor-beta type I receptor gene in head-and-neck cancer metastases.
Chen T et al.
International Journal of Cancer, 2001
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