Associated Papers
Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53.
Malkomes P et al.
Oncogene, 2021
Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs.
Cho SY et al.
Life Science Alliance, 2020
Spotlight on the transglutaminase 2 gene: a focus on genomic and transcriptional aspects.
Bianchi N et al.
The Biochemical Journal, 2018
Renal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagy.
Kang JH et al.
Cell Death & Disease, 2016
Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation.
Yeo SY et al.
Elife, 2016
Isopeptidase activity of human transglutaminase 2: disconnection from transamidation and characterization by kinetic parameters.
Király R et al.
Amino Acids, 2016
PINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation.
Min B et al.
Journal of Neuroscience Research, 2015
Cancer cells promote survival through depletion of the von Hippel-Lindau tumor suppressor by protein crosslinking.
Kim DS et al.
Oncogene, 2011
Bcr is a substrate for Transglutaminase 2 cross-linking activity.
Yi SJ et al.
Bmc Biochemistry, 2011
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.
Luciani A et al.
Nature Cell Biology, 2010
Cystamine suppresses polyalanine toxicity in a mouse model of oculopharyngeal muscular dystrophy.
Davies JE et al.
Science Translational Medicine, 2010
Transglutaminase 2 regulates the GTPase-activating activity of Bcr.
Yi SJ et al.
The Journal of Biological Chemistry, 2009
Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis.
Király R et al.
The Febs Journal, 2009
[Implications of successful immunotherapy in ALS model mice].
Urushitani M
Brain and Nerve = Shinkei Kenkyu No Shinpo, 2008
Tissue transglutaminase regulates focal adhesion kinase/AKT activation by modulating PTEN expression in pancreatic cancer cells.
Verma A et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2008
Missense mutations in the TGM2 gene encoding transglutaminase 2 are found in patients with early-onset type 2 diabetes. Mutation in brief no. 982. Online.
Porzio O et al.
Human Mutation, 2007
Crosslinking and G-protein functions of transglutaminase 2 contribute differentially to fibroblast wound healing responses.
Stephens P et al.
Journal of Cell Science, 2004
Site-directed mutagenesis of human tissue transglutaminase: Cys-277 is essential for transglutaminase activity but not for GTPase activity.
Lee KN et al.
Biochimica Et Biophysica Acta, 1993