Associated Papers
Structural basis for T-cell intracellular antigen-1 amyloid fibril formation revealed by cryo-electron microscopy.
Inaoka D et al.
Pnas Nexus, 2025
Axonopathy Underlying Amyotrophic Lateral Sclerosis: Unraveling Complex Pathways and Therapeutic Insights.
Luan T et al.
Neuroscience Bulletin, 2024
Decoding Missense Variants by Incorporating Phase Separation via Machine Learning.
Feng M et al.
Nature Communications, 2024
39333476 (PubMed )
Supplement: 41467_2024_52580_MOESM4_ESM.xlsx › impact_ps_mutations
Stress-mediated aggregation of disease-associated proteins in amyloid bodies.
Chandhok S et al.
Scientific Reports, 2023
Valosin containing protein (VCP): initiator, modifier, and potential drug target for neurodegenerative diseases.
Chu S et al.
Molecular Neurodegeneration, 2023
Targeting the NEDP1 enzyme to ameliorate ALS phenotypes through stress granule disassembly.
Kassouf T et al.
Science Advances, 2023
ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures.
Sekiyama N et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022
Pathological phase transitions in ALS-FTD impair dynamic RNA-protein granules.
Nedelsky NB et al.
Rna (new York, N.y.), 2022
Stress granule subtypes: an emerging link to neurodegeneration.
Advani VM et al.
Cellular and Molecular Life Sciences : Cmls, 2020
ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.
Wang B et al.
Molecular Cell, 2019
No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients.
Baradaran-Heravi Y et al.
Neurobiology of Aging, 2018
Stress Granules and ALS: A Case of Causation or Correlation?
Fernandes N et al.
Advances in Neurobiology, 2018
Clinical and neuropathological features of ALS/FTD with TIA1 mutations.
Hirsch-Reinshagen V et al.
Acta Neuropathologica Communications, 2017
TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Mackenzie IR et al.
Neuron, 2017
Unraveling the multifaceted insights into amyotrophic lateral sclerosis: Genetic underpinnings, pathogenesis, and therapeutic horizons.
Sharma R et al.
Mutation Research. Reviews in Mutation Research, 0
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