Varaico: Literature-Extracted Genetic Variants

Gene:TIAM1
Variant:p.A441G
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TIAM1

NM_001353694.2:p.A441G

Associated Papers

Mechanisms and consequences of dysregulation of the Tiam family of Rac activators in disease.

Maltas J et al.

Biochemical Society Transactions, 2020

The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module.

Terawaki S et al.

The Embo Journal, 2010

19893486 (PubMed )
Supplement: emboj2009323s3.pdf

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors.

Rossman KL et al.

Nature Reviews. Molecular Cell Biology, 2005

Tiam1 mutations in human renal-cell carcinomas.

Engers R et al.

International Journal of Cancer, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."