Varaico: Literature-Extracted Genetic Variants

Gene:TIE1
Variant:p.K870R
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TIE1

NM_005424.5:p.K870R

Associated Papers

TIE1-dependent lymphatic vascular remodeling is mediated by its second tyrosine kinase domain.

Baldwin HS et al.

Development (cambridge, England), 2025

Loss-of-function mutations of the TIE1 receptor tyrosine kinase cause late-onset primary lymphedema.

Brouillard P et al.

The Journal of Clinical Investigation, 2024

LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis.

Xu M et al.

Cell, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."