Varaico: Literature-Extracted Genetic Variants

Gene:TIFA
Variant:p.E178A
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TIFA

NM_052864.3:p.E178A

Associated Papers

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC.

Snelling T et al.

The Biochemical Journal, 2022

TIFA activates IkappaB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6.

Ea CK et al.

Proceedings of the National Academy of Sciences of the United States of America, 2004

Identification of TIFA as an adapter protein that links tumor necrosis factor receptor-associated factor 6 (TRAF6) to interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK-1) in IL-1 receptor signaling.

Takatsuna H et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."