Varaico: Literature-Extracted Genetic Variants

Gene:TIMP1
Variant:p.F124F
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TIMP1

NM_003254.3:p.F124F

Associated Papers

Analysis of the Role of Gene Variants in Matrix Metalloproteinases and Their Tissue Inhibitors in Bronchopulmonary Dysplasia (BPD): A Study in the Polish Population.

Szpecht D et al.

Current Issues in Molecular Biology, 2025

Association Between Genetic Variants and Circulating Biomarkers of Extracellular Matrix Remodelling in Indian Patients With Acute and Recurrent Myocardial Infarction.

Singh R et al.

Journal of Lipid and Atherosclerosis, 2025

Genetic Determinants of Colonic Diverticulosis-A Systematic Review.

Nehring P et al.

Genes, 2025

Comprehensive Analysis of the Role of Gene Variants in Matrix Metalloproteinases and Their Tissue Inhibitors in Retinopathy of Prematurity: A Study in the Polish Population.

Choręziak-Michalak A et al.

International Journal of Molecular Sciences, 2023

High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors.

Shiau CK et al.

Nature Communications, 2023

37433798 (PubMed )
Supplement: 41467_2023_39813_MOESM3_ESM.zip › Supplementary_Data › Supplementary_Data14_Fibroblasts_expanded_mutations.xlsx › Supplemental_Data_14

Polymorphisms and gene expression of metalloproteinases and their inhibitors associated with cerebral ischemic stroke in young patients with sickle cell anemia.

do Kleyton Palmeira Ó et al.

Molecular Biology Reports, 2023

Functionally significant polymorphisms of the MMP9 gene are associated with primary open-angle glaucoma in the population of Russia.

Ponomarenko I et al.

European Journal of Ophthalmology, 2022

35254145 (PubMed )
Supplement: sj-doc-7-ejo-10.1177_11206721221083722.doc

Effects of TIMP1 rs4898 Gene Polymorphism on Early-Onset Preeclampsia Development and Placenta Weight.

Mrozikiewicz AE et al.

Diagnostics (basel, Switzerland), 2022

MMP-1 (519 A/G) and TIMP-1 (372 T/C) genes polymorphism in an Egyptian sample of Acne vulgaris patients.

Mohammed SMA et al.

Journal of Cosmetic Dermatology, 2022

The polymorphisms of extracellular matrix-remodeling genes are associated with pelvic organ prolapse.

Li L et al.

International Urogynecology Journal, 2022

34973089 (PubMed )
Supplement: 192_2021_4917_MOESM1_ESM.xls › Sheet1

Genetic variants of tissue inhibitors of matrix metalloproteinase 1 (rs4898) and 2 (rs8179090) in diverticulosis.

Nehring P et al.

European Journal of Gastroenterology & Hepatology, 2021

TIMP1 and TIMP3 circulating levels and promoter polymorphisms in breast cancer.

Balkhi S et al.

British Journal of Biomedical Science, 2021

Thrombomodulin gene polymorphism and the occurrence and prognostic value of sepsis acute kidney injury.

Li Q et al.

Medicine, 2021

Association of Gene Polymorphisms With Primary Open Angle Glaucoma: A Systematic Review and Meta-Analysis.

Chen M et al.

Investigative Ophthalmology & Visual Science, 2019

Relationship of polymorphisms in the tissue inhibitor of metalloproteinase (TIMP)-1 and -2 genes with chronic heart failure.

Polina ER et al.

Scientific Reports, 2018

Altered Expression Levels of MMP1, MMP9, MMP12, TIMP1, and IL-1β as a Risk Factor for the Elevated IOP and Optic Nerve Head Damage in the Primary Open-Angle Glaucoma Patients.

Markiewicz L et al.

Biomed Research International, 2015

Matrix metalloproteinase (MMP)-8 and tissue inhibitor of MMP-1 (TIMP-1) gene polymorphisms in generalized aggressive periodontitis: gingival crevicular fluid MMP-8 and TIMP-1 levels and outcome of periodontal therapy.

Emingil G et al.

Journal of Periodontology, 2014

Role of plasma matrix-metalloproteases (MMPs) and their polymorphisms (SNPs) in sepsis development and outcome in ICU patients.

Martin G et al.

Scientific Reports, 2014

Gene polymorphisms of the MMP1, MMP9, MMP12, IL-1β and TIMP1 and the risk of primary open-angle glaucoma.

Markiewicz L et al.

Acta Ophthalmologica, 2013

Exposure to environmental tobacco smoke, human E-cadherin C-160A polymorphism, and childhood asthma.

Wang MF et al.

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, 2013

Association of TIMP-1 and TIMP-2 gene polymorphisms with progression of liver fibrosis in patients with type C chronic liver disease.

Ikebuchi Y et al.

Biochemical Genetics, 2013

TIMP-1 gene polymorphism: are genetics able to predict outcome of septic patients?

Behnes M et al.

Critical Care (london, England), 2013

The 372 T/C genetic polymorphism of TIMP-1 is associated with serum levels of TIMP-1 and survival in patients with severe sepsis.

Lorente L et al.

Critical Care (london, England), 2013

Association of TIMP-1 +372 SNP with digital ulcer manifestation in female systemic sclerosis patients.

Skarmoutsou E et al.

Human Immunology, 2012

Combinatorial effect of TIMP-1 and α1AT gene polymorphisms on development of chronic obstructive pulmonary disease.

Kumar M et al.

Clinical Biochemistry, 2011

Association of MMP1-1607 1G/2G and TIMP1 372 T/C gene polymorphisms with risk of primary open angle glaucoma in a Polish population.

Majsterek I et al.

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 2011

Genetic polymorphisms of the matrix metalloproteinase-3 (MMP-3) and tissue inhibitors of matrix metalloproteinases-1 (TIMP-1) modulate the development of ankylosing spondylitis.

Wei JC et al.

Annals of the Rheumatic Diseases, 2009

Genetic polymorphism of the tissue inhibitor of metalloproteinase-1 is associated with an increased risk of endometrial cancer.

Yi YC et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2009

Tissue inhibitor of metalloproteinase-1 (TIMP-1) polymorphisms in a Caucasian population with abdominal aortic aneurysm.

Hinterseher I et al.

World Journal of Surgery, 2007

Role of matrix metalloproteinase, tissue inhibitor of metalloproteinase and tumor necrosis factor-alpha single nucleotide gene polymorphisms in inflammatory bowel disease.

Meijer MJ et al.

World Journal of Gastroenterology, 2007

Analysis of TIMP-1 gene polymorphisms in Italian sclerodermic patients.

Indelicato M et al.

Journal of Clinical Laboratory Analysis, 2006

Tissue inhibitor of metalloproteinases-1, -2, and -3 polymorphisms in a white population with intracranial aneurysms.

Krex D et al.

Stroke, 2003

Association of TIMP-1 and COL4A4 Gene Polymorphisms with Keratoconus in an Iranian Population.

Yari D et al.

Journal of Ophthalmic & Vision Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."