Associated Papers
IFN-γ-induced trained immunity enhances killing of priority pathogens in healthy and genetically vulnerable individuals.
Murphy DM et al.
Jci Insight, 2026
Immunomodulatory effects of the TIRAP/MAL rs8177374 (S180L) variant: Meta-Analytic evidence from severe and Plasmodium falciparum malaria.
González-Castillo NI et al.
Microbial Pathogenesis, 2026
Family-based genetics identifies association of CUBN, IL1RL1 and PRKN variants with leprosy in Bangladesh.
Dos Santos AM et al.
Scientific Reports, 2025
Genetic Factors Associated With Myocardial Infarction in Saudi Arabia.
Saeed A et al.
Journal of the Saudi Heart Association, 2025
Polymorphisms in Immune Genes and Their Association with Tuberculosis Susceptibility: An Analysis of the African Population.
Wodelo W et al.
The Application of Clinical Genetics, 2024
Role of MyD88-Adaptor-Like (MAL) Gene Polymorphism rs8177374 and Cytokine (IFN-γ, TNF-α, IL-10, TGF-β) Levels in Diverse Malaria Manifestations upon P. falciparum and P. vivax Infections.
Rani A et al.
Japanese Journal of Infectious Diseases, 2023
Macrophage transcription factor TonEBP promotes systemic lupus erythematosus and kidney injury via damage-induced signaling pathways.
Yoo EJ et al.
Kidney International, 2023
Systemic lupus erythematosus and toll-like receptor 9 polymorphisms: A meta-analysis of genetic association studies.
Lee YH et al.
Lupus, 2023
Genetic characteristics of common variable immunodeficiency patients with autoimmunity.
Liu Z et al.
Frontiers in Genetics, 2023
IL-1 Superfamily Member (IL-1A, IL-1B and IL-18) Genetic Variants Influence Susceptibility and Clinical Course of Mediterranean Spotter Fever.
Scola L et al.
Biomolecules, 2022
Toll-Like Receptors and Mannose Binding Lectin Gene Polymorphisms Associated with Cryptosporidial Diarrhea in Children in Southern India.
Liakath FB et al.
The American Journal of Tropical Medicine and Hygiene, 2021
Prognostic Impact of Genetic Variants of MECP2 and TIRAP on Clinical Outcomes of Systemic Lupus Erythematosus with and without Nephritis.
Tayel SI et al.
Biomolecules, 2021
Protective role of TIRAP functional variant against development of coronary artery disease.
Noreen M et al.
Saudi Journal of Biological Sciences, 2021
Polymorphism of genes associated with infectious lung diseases in Northern Asian populations and in patients with community-acquired pneumonia.
Mikhailova SV et al.
Vavilovskii Zhurnal Genetiki I Selektsii, 2021
Association of variants in selected genes mediating host immune response with duration of Staphylococcus aureus bacteremia.
Carter TC et al.
Genes and Immunity, 2020
Association of two polymorphisms Asp299Gly and Thr399Ile in Toll-like receptor 4 with rheumatoid arthritis: A meta-analysis.
Yan S et al.
International Journal of Rheumatic Diseases, 2020
MAL adaptor (TIRAP) S180L polymorphism and severity of disease among tuberculosis patients.
Saranathan R et al.
Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2020
Host genetic variability and pneumococcal disease: a systematic review and meta-analysis.
Kloek AT et al.
Bmc Medical Genomics, 2019
Common variants of genes encoding TLR4 and TLR4 pathway members TIRAP and IRAK1 are effective on MCP1, IL6, IL1β, and TNFα levels in type 2 diabetes and insulin resistance.
Degirmenci I et al.
Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.], 2019
TNF-α promoter polymorphisms (G-238A and G-308A) are associated with susceptibility to Systemic Lupus Erythematosus (SLE) and P. falciparum malaria: a study in malaria endemic area.
Mahto H et al.
Scientific Reports, 2019
A Toll-like receptor 2 genetic variant modulates occurrence of bacterial infections in patients with sickle cell disease.
Tozatto-Maio K et al.
British Journal of Haematology, 2019
Host genetic variants in sepsis risk: a field synopsis and meta-analysis.
Lu H et al.
Critical Care (london, England), 2019
Genetics of Malaria Inflammatory Responses: A Pathogenesis Perspective.
Penha-Gonçalves C
Frontiers in Immunology, 2019
Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children.
Siebert JN et al.
Frontiers in Immunology, 2018
Single nucleotide polymorphisms of nucleotide excision repair pathway are significantly associated with outcomes of platinum-based chemotherapy in lung cancer.
Song X et al.
Scientific Reports, 2017
Associations between PTPN22 and TLR9 polymorphisms and systemic lupus erythematosus: a comprehensive meta-analysis.
Hu LY et al.
Archives of Dermatological Research, 2017
Matrix Metalloproteinase-9 rs17576 Gene Polymorphism and Behçet's Disease: Is There an Association?
Kamal A et al.
Immunological Investigations, 2017
Genetic selection pressure in TLR9 gene may enforce risk for SLE in Indian Tamils.
Yusuf JH et al.
Lupus, 2017
Whole genome sequencing of one complex pedigree illustrates challenges with genomic medicine.
Fang H et al.
Bmc Medical Genomics, 2017
Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome.
Halabi S et al.
The Journal of Biological Chemistry, 2017
MEFV M694V mutation has a role in susceptibility to ankylosing spondylitis: A meta-analysis.
Zhong L et al.
Plos One, 2017
Association of TLR variants with susceptibility to Plasmodium vivax malaria and parasitemia in the Amazon region of Brazil.
Costa AG et al.
Plos One, 2017
Heterozygous mutants of TIRAP (S180L) polymorphism protect adult patients with Plasmodium falciparum infection against severe disease and mortality.
Panda AK et al.
Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2016
Association between toll-like receptor polymorphisms and systemic lupus erythematosus: a meta-analysis update.
Lee YH et al.
Lupus, 2016
TLR9 polymorphisms and systemic lupus erythematosus risk: an update meta-analysis study.
Wang D et al.
Rheumatology International, 2016
A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.
Ní Cheallaigh C et al.
Immunity, 2016
Genetic predisposition of variants in TLR2 and its co-receptors to severe malaria in Odisha, India.
Panigrahi S et al.
Immunologic Research, 2016
Application of Various Statistical Models to Explore Gene-Gene Interactions in Folate, Xenobiotic, Toll-Like Receptor and STAT4 Pathways that Modulate Susceptibility to Systemic Lupus Erythematosus.
Rupasree Y et al.
Molecular Diagnosis & Therapy, 2016
TLR4/TIRAP polymorphisms are associated with progression and survival of patients with symptomatic myeloma.
Bagratuni T et al.
British Journal of Haematology, 2016
The influence of genetic polymorphisms in TLR4 and TIRAP, and their expression levels in peripheral blood, on susceptibility to sepsis.
Zhang J et al.
Experimental and Therapeutic Medicine, 2016
A toll-like receptor 9 (rs352140) variant is associated with placental inflammation in newborn infants.
Karody V et al.
The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2016
Preliminary evaluation of exome sequencing to identify genetic markers of susceptibility to tuberculosis disease.
Duncan C et al.
Bmc Research Notes, 2015
Gene/environment interactions in the pathogenesis of autoimmunity: new insights on the role of Toll-like receptors.
Gianchecchi E et al.
Autoimmunity Reviews, 2015
Association of estrogen receptor 1 (ESR1) haplotypes with risk for systemic lupus erythematosus among South Indians.
Rupasree Y et al.
Indian Journal of Experimental Biology, 2015
Genetic Variation in Pattern Recognition Receptors and Adaptor Proteins Associated With Development of Chronic Q Fever.
Schoffelen T et al.
The Journal of Infectious Diseases, 2015