Varaico: Literature-Extracted Genetic Variants

Gene:TIRAP
Variant:p.A186A
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TIRAP

NM_001318777.2:p.A186A

Associated Papers

Common variants of genes encoding TLR4 and TLR4 pathway members TIRAP and IRAK1 are effective on MCP1, IL6, IL1β, and TNFα levels in type 2 diabetes and insulin resistance.

Degirmenci I et al.

Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.], 2019

Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei.

Dickey AK et al.

Plos Neglected Tropical Diseases, 2019

Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility.

Noreen M et al.

Immunologic Research, 2015

TIRAP C539T polymorphism contributes to tuberculosis susceptibility: evidence from a meta-analysis.

Liu Q et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2014

The MyD88 rs6853 and TIRAP rs8177374 polymorphic sites are associated with resistance to human pulmonary tuberculosis.

Capparelli R et al.

Genes and Immunity, 2013

Impaired TLR5 functionality is associated with survival in melioidosis.

West TE et al.

Journal of Immunology (baltimore, Md. : 1950), 2013

Toll-like receptors and human disease: lessons from single nucleotide polymorphisms.

Lin YT et al.

Current Genomics, 2012

Innate immune gene polymorphisms in tuberculosis.

Azad AK et al.

Infection and Immunity, 2012

Genetic variation in Toll-like receptors and disease susceptibility.

Netea MG et al.

Nature Immunology, 2012

Common polymorphisms in the PKP3-SIGIRR-TMEM16J gene region are associated with susceptibility to tuberculosis.

Horne DJ et al.

The Journal of Infectious Diseases, 2012

Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis.

West TE et al.

Genes and Immunity, 2012

Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data.

Baker AR et al.

Plos One, 2012

TIRAP polymorphisms and TB susceptibility.

Denholm JT et al.

Tuberculosis (edinburgh, Scotland), 2011

Genetic variations in MyD88 adaptor-like are associated with atopic dermatitis.

An Y et al.

International Journal of Molecular Medicine, 2011

Association of TIRAP (MAL) gene polymorhisms with susceptibility to tuberculosis in a Chinese population.

Zhang YX et al.

Genetics and Molecular Research : Gmr, 2011

Genetic variants in the TIRAP gene are associated with increased risk of sepsis-associated acute lung injury.

Song Z et al.

Bmc Medical Genetics, 2010

Toll-like receptor and TIRAP gene polymorphisms in pulmonary tuberculosis patients of South India.

Selvaraj P et al.

Tuberculosis (edinburgh, Scotland), 2010

Genetic susceptibility to different clinical forms of tuberculosis in the Peruvian population.

Taype CA et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2010

Polymorphisms in IL-1beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis.

Motsinger-Reif AA et al.

Bmc Medical Genetics, 2010

Genetic risk for recurrent urinary tract infections in humans: a systematic review.

Zaffanello M et al.

Journal of Biomedicine & Biotechnology, 2010

Polymorphic variation in TIRAP is not associated with susceptibility to childhood TB but may determine susceptibility to TBM in some ethnic groups.

Dissanayeke SR et al.

Plos One, 2009

The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis.

Caws M et al.

Plos Pathogens, 2008

Toll-like receptor polymorphisms and susceptibility to human disease.

Misch EA et al.

Clinical Science (london, England : 1979), 2008

Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter?

Berrington WR et al.

Immunological Reviews, 2007

A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis.

Thuong NT et al.

Genes and Immunity, 2007

A polymorphism in Toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis.

Hawn TR et al.

The Journal of Infectious Diseases, 2006

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