Varaico: Literature-Extracted Genetic Variants

Gene:TLN1
Variant:p.R2526G
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TLN1

NM_006289.4:p.R2526G

Associated Papers

Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation.

Goult BT et al.

Journal of Structural Biology, 2013

Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics.

Bate N et al.

Plos One, 2012

Control of high affinity interactions in the talin C terminus: how talin domains coordinate protein dynamics in cell adhesions.

Himmel M et al.

The Journal of Biological Chemistry, 2009

The conserved C-terminal I/LWEQ module targets Talin1 to focal adhesions.

Franco SJ et al.

Cell Motility and the Cytoskeleton, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."