Varaico: Literature-Extracted Genetic Variants

Gene:TLN1
Variant:p.L325R
Back to variants list

TLN1

NM_006289.4:p.L325R

Associated Papers

Caveolae couple mechanical stress to integrin recycling and activation.

Lolo FN et al.

Elife, 2022

Frontline Science: A flexible kink in the transmembrane domain impairs β2 integrin extension and cell arrest from rolling.

Sun H et al.

Journal of Leukocyte Biology, 2020

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity.

Elosegui-Artola A et al.

Nature Cell Biology, 2016

The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering.

Ellis SJ et al.

Plos Genetics, 2014

Optogenetics-based localization of talin to the plasma membrane promotes activation of β3 integrins.

Liao Z et al.

The Journal of Biological Chemistry, 0

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."