Varaico: Literature-Extracted Genetic Variants

Gene:TLR1
Variant:p.S602I
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TLR1

NM_003263.4:p.S602I

Associated Papers

Tumor evolution and immune microenvironment dynamics in primary and relapsed mantle cell lymphoma.

Wan H et al.

Cell Reports. Medicine, 2025

40876452 (PubMed )
Supplement: mmc2.xlsx › TableS3._Nonsilent_mutations

Genetic Predisposition of TLR 1 and TLR 6 Polymorphisms to Schizophrenia Onset and Prediction of Treatment Response.

Aflouk Y et al.

Biochemical Genetics, 2025

Genetic polymorphisms of TLR1, TLR2, TLR3 and TLR4 in patients with recurrent or severe infections.

Teräsjärvi J et al.

International Journal of Immunogenetics, 2024

SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease.

Strausz S et al.

Nature Communications, 2024

Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.

Yang N et al.

Bmc Pediatrics, 2024

38310242 (PubMed )
Supplement: 12887_2024_4553_MOESM1_ESM.xlsx › trio.hg38.filter

Polymorphisms in Immune Genes and Their Association with Tuberculosis Susceptibility: An Analysis of the African Population.

Wodelo W et al.

The Application of Clinical Genetics, 2024

Bioinformatics analysis to identify the relationship between human papillomavirus-associated cervical cancer, toll-like receptors and exomes: A genetic epidemiology study.

Gomes FC et al.

Plos One, 2024

39208235 (PubMed )
Supplement: pone.0305760.s001.xlsx › Supplement_4_-_Genetic_variants

Association between polymorphisms of TLR2-1-6 and bipolar disorder in a tunisian population.

Aflouk Y et al.

Molecular Biology Reports, 2023

Genetic analysis and prenatal diagnosis of short-rib thoracic dysplasia 3 with or without polydactyly caused by compound heterozygous variants of DYNC2H1 gene in four Chinese families.

Fang Y et al.

Frontiers in Genetics, 2023

37007936 (PubMed )
Supplement: Table1.XLS › Sheet

Exome variants associated with asthma and allergy.

Wjst M

Scientific Reports, 2022

36470944 (PubMed )
Supplement: 41598_2022_24960_MOESM1_ESM.pdf

Pharmacogenetics Role of Genetic Variants in Immune-Related Factors: A Systematic Review Focusing on mCRC.

Scarabel L et al.

Pharmaceutics, 2022

Predicting drug response and toxicity in metastatic colorectal cancer: the role of germline markers.

Bignucolo A et al.

Expert Review of Clinical Pharmacology, 2022

Novel neutrophil phenotypic signature in pediatric patients with type 1 diabetes and diabetic ketoacidosis.

Nichols BE et al.

Journal of Leukocyte Biology, 2022

Systematic review and meta-analysis of human Toll-like receptors genetic polymorphisms for susceptibility to tuberculosis infection.

Varshney D et al.

Cytokine, 2022

The Genetic Association Between TLR-1, -2, -4, and -6 Gene Polymorphisms and Rheumatoid Arthritis Susceptibility in a Chinese Han Population.

Peng Y et al.

Genetic Testing and Molecular Biomarkers, 2022

Genetic polymorphisms of toll-like receptors in leprosy patients from southern Brazil.

Masin PS et al.

Frontiers in Genetics, 2022

Deep resequencing identifies candidate functional genes in leprosy GWAS loci.

Fava VM et al.

Plos Neglected Tropical Diseases, 2021

34879060 (PubMed )
Supplement: pntd.0010029.s004.xlsx › S2_Table

Synergistic effect of genetic polymorphisms in TLR6 and TLR10 genes on the risk of pulmonary tuberculosis in a Moldavian population.

Varzari A et al.

Innate Immunity, 2021

Why does SARS-CoV-2 hit in different ways? Host genetic factors can influence the acquisition or the course of COVID-19.

Monticelli M et al.

European Journal of Medical Genetics, 2021

33872774 (PubMed )
Supplement: mmc2.xlsx › Foglio1

Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia.

Fontana D et al.

Hemasphere, 2020

33196013 (PubMed )
Supplement: hs9-4-e497-s005.xlsx › Sheet1

A novel patient-derived organoids-based xenografts model for preclinical drug response testing in patients with colorectal liver metastases.

Jian M et al.

Journal of Translational Medicine, 2020

32532289 (PubMed )
Supplement: 12967_2020_2407_MOESM2_ESM.xlsx › Table_S1A_356_SNV

Age-of-onset information helps identify 76 genetic variants associated with allergic disease.

Ferreira MAR et al.

Plos Genetics, 2020

32603359 (PubMed )
Supplement: pgen.1008725.s024.xls › Supp_Table_11

IL-4 polymorphism influences susceptibility to Pneumocystis jirovecii pneumonia in HIV-positive patients.

Wójtowicz A et al.

Aids (london, England), 2019

Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease.

Fava VM et al.

Proceedings of the National Academy of Sciences of the United States of America, 2019

31308240 (PubMed )
Supplement: pnas.1901805116.sd01.xlsx › Sheet1

Pattern recognition receptor polymorphisms in early periodontitis.

Leite FRM et al.

Journal of Periodontology, 2019

Host genetic variants in sepsis risk: a field synopsis and meta-analysis.

Lu H et al.

Critical Care (london, England), 2019

30683156 (PubMed )
Supplement: 13054_2019_2313_MOESM3_ESM.docx

Toll-like receptor 2, 4 and 9 polymorphisms and their association with ICU-acquired infections in Central Greece.

Chatzi M et al.

Journal of Critical Care, 2018

Variants of TLR1 associated with tuberculosis susceptibility in the Chinese Tibetan population but not in Han Chinese.

Zhang M et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2018

Toll-like receptor variants and cervical Atopobium vaginae infection in women with pelvic inflammatory disease.

Taylor BD et al.

American Journal of Reproductive Immunology (new York, N.y. : 1989), 2018

Toll-like receptor 1 and 10 gene polymorphisms are linked to postbronchiolitis asthma in adolescence.

Törmänen S et al.

Acta Paediatrica (oslo, Norway : 1992), 2018

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.

Ferreira MA et al.

Nature Genetics, 2017

29083406 (PubMed )
Supplement: NIHMS74439-supplement-Supplementary_tables.xlsx › ST12

Lessons from ten years of genome-wide association studies of asthma.

Vicente CT et al.

Clinical & Translational Immunology, 2017

29333270 (PubMed )
Supplement: cti201754x1.zip › CTI-17-REV-0041V1-s01.xls › Supplementary_Table_6

Evaluation of Toll-like-receptor gene family variants as prognostic biomarkers in rheumatoid arthritis.

Torices S et al.

Immunology Letters, 2017

Genetic variation of the Toll-like receptors in a Swedish allergic rhinitis case population.

Henmyr V et al.

Bmc Medical Genetics, 2017

28228119 (PubMed )
Supplement: 12881_2017_379_MOESM8_ESM.xlsx › TabS4

Rapid detection of functional gene polymorphisms of TLRs and IL-17 using high resolution melting analysis.

Teräsjärvi J et al.

Scientific Reports, 2017

TLR1 polymorphism rs4833095 as a risk factor for IgA nephropathy in a Chinese Han population: A case-control study.

Gao J et al.

Oncotarget, 2016

Rapidity of fibrosis progression in liver transplant recipients with recurrent hepatitis C is influenced by toll-like receptor 3 polymorphism.

Citores MJ et al.

Clinical Transplantation, 2016

Detection and interpretation of shared genetic influences on 42 human traits.

Pickrell JK et al.

Nature Genetics, 2016

27182965 (PubMed )
Supplement: NIHMS780506-supplement-6.pdf

A Common Genetic Variant in TLR1 Enhances Human Neutrophil Priming and Impacts Length of Intensive Care Stay in Pediatric Sepsis.

Whitmore LC et al.

Journal of Immunology (baltimore, Md. : 1950), 2016

Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes.

Deschamps M et al.

American Journal of Human Genetics, 2016

Toll-like receptor cascade and gene polymorphism in host-pathogen interaction in Lyme disease.

Rahman S et al.

Journal of Inflammation Research, 2016

Associations of Toll-Like Receptor and β-Defensin Polymorphisms with Measures of Periodontal Disease (PD) in HIV+ North American Adults: An Exploratory Study.

Mehlotra RK et al.

Plos One, 2016

Preliminary evaluation of exome sequencing to identify genetic markers of susceptibility to tuberculosis disease.

Duncan C et al.

Bmc Research Notes, 2015

Association of 4p14 TLR locus with antibodies to Helicobacter pylori.

Sung H et al.

Genes and Immunity, 2015

Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility.

Noreen M et al.

Immunologic Research, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."