Varaico: Literature-Extracted Genetic Variants

Gene:TLR2
Variant:p.A53T
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TLR2

NM_001318789.2:p.A53T

Associated Papers

Alpha-Synuclein Neurobiology in Parkinson's Disease: A Comprehensive Review of Its Role, Mechanisms, and Therapeutic Perspectives.

Pitton Rissardo J et al.

Brain Sciences, 2025

The Aggregation Continuum of α-Synuclein and Its Relevance to Brain Aging.

Rana A et al.

Acs Chemical Neuroscience, 2025

A small molecule toll-like receptor antagonist rescues α-synuclein fibril pathology.

Chedid J et al.

The Journal of Biological Chemistry, 2022

Role of lysosomes in physiological activities, diseases, and therapy.

Zhang Z et al.

Journal of Hematology & Oncology, 2021

Targeting Microglial and Neuronal Toll-like Receptor 2 in Synucleinopathies.

Kwon S et al.

Experimental Neurobiology, 2019

Glia and alpha-synuclein in neurodegeneration: A complex interaction.

Brück D et al.

Neurobiology of Disease, 2016

Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy.

Kim C et al.

Cell Reports, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."