Varaico: Literature-Extracted Genetic Variants

Gene:TLR2
Variant:p.N199N
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TLR2

NM_001318789.2:p.N199N

Associated Papers

Protective Association of TLR6 rs5743810 with Pulmonary Tuberculosis in the Population of JAMMU Region.

Sharma S et al.

Indian Journal of Microbiology, 2026

Impact of Sociodemographic, Clinical, and Genetic Factors and Fusobacterium nucleatum on Premature Birth Outcomes in Women from Kazakhstan: A Case-Control Study.

Zhurabekova G et al.

Iranian Journal of Medical Sciences, 2025

Pharmacogenomics of TNF inhibitors.

Jan Z et al.

Frontiers in Immunology, 2025

Pharmacogenomic landscape of TNF inhibitors in the Middle Eastern Qatari population.

Jan Z et al.

Frontiers in Immunology, 2025

41346622 (PubMed )
Supplement: Table2.xlsx › Supplementary_Table_8

Association of the Single Nucleotide Polymorphism 19216T/C in the TLR2 Gene (rs3804099) with Entamoeba histolytica/Entamoeba dispar/Entamoeba moshkovskii Infection Among Lebanese Children.

Dib I et al.

Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research, 2024

Polymorphisms in Immune Genes and Their Association with Tuberculosis Susceptibility: An Analysis of the African Population.

Wodelo W et al.

The Application of Clinical Genetics, 2024

Relevance of Coding Variation in FLG And DOCK8 in Finnish Pediatric Patients with Early-Onset Moderate-To-Severe Atopic Dermatitis.

Perälä M et al.

Jid Innovations : Skin Science From Molecules to Population Health, 2023

37533579 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_S1

Synonymous Variants: Necessary Nuance in Our Understanding of Cancer Drivers and Treatment Outcomes.

Kaissarian NM et al.

Journal of the National Cancer Institute, 2022

Variations within Toll-like receptor (TLR) and TLR signaling pathway-related genes and their synergistic effects on the risk of Guillain-Barré syndrome.

Dutta D et al.

Journal of the Peripheral Nervous System : Jpns, 2022

Systematic review and meta-analysis of human Toll-like receptors genetic polymorphisms for susceptibility to tuberculosis infection.

Varshney D et al.

Cytokine, 2022

Association of TLR2 and TLR4 gene polymorphism with susceptibility to wart infections and their response to candida antigen immunotherapy.

Tantawy EA et al.

The Journal of Dermatological Treatment, 2022

Deciphering Genetic Susceptibility to Tuberculous Meningitis.

Schurz H et al.

Frontiers in Neurology, 2022

Toll-Like Receptors (TLRs): Structure, Functions, Signaling, and Role of Their Polymorphisms in Colorectal Cancer Susceptibility.

Sameer AS et al.

Biomed Research International, 2021

Genetic Analysis of TB Susceptibility Variants in Ghana Reveals Candidate Protective Loci in SORBS2 and SCL11A1 Genes.

Asante-Poku A et al.

Frontiers in Genetics, 2021

Polymorphisms in Toll-like receptors 1, 2, 5, and 10 are associated with predisposition to Helicobacter pylori infection.

Kalkanli Tas S et al.

European Journal of Gastroenterology & Hepatology, 2020

-196 to -174del, rs4696480, rs3804099 polymorphisms of Toll-like receptor 2 gene impact the susceptibility of cancers: evidence from 37053 subjects.

Gao SL et al.

Bioscience Reports, 2019

Toll-like receptor polymorphism in host immune response to infectious diseases: A review.

Mukherjee S et al.

Scandinavian Journal of Immunology, 2019

Genetic variation in TLR pathway and the risk of pulmonary tuberculosis in a Moldavian population.

Varzari A et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2019

The Interplay of Human and Mycobacterium Tuberculosis Genomic Variability.

Correa-Macedo W et al.

Frontiers in Genetics, 2019

Association of VDR gene polymorphisms and 22 bp deletions in the promoter region of TLR2Δ22 (-196-174) with increased risk of pulmonary tuberculosis: A case-control study in tea garden communities of Assam.

Devi KR et al.

Journal of Clinical Laboratory Analysis, 2018

Association of a single nucleotide polymorphism in the TLR2 gene (rs3804099), but not in the TLR4 gene (rs4986790), with Helicobacter pylori infection and peptic ulcer.

Mirkamandar E et al.

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology, 2018

Potential role of Toll-like receptor 2 expression and polymorphisms in colon cancer susceptibility in the Saudi Arabian population.

Semlali A et al.

Oncotargets and Therapy, 2018

Human genetic factors in tuberculosis: an update.

van Tong H et al.

Tropical Medicine & International Health : Tm & Ih, 2017

Polymorphisms of toll-like receptors 2 and 9 and severity and prognosis of bacterial meningitis in Chinese children.

Zhang P et al.

Scientific Reports, 2017

No genetic relationship between TLR2 rs4696480, rs3804100, and rs3804099 gene polymorphisms and female breast cancer in Saudi populations.

Semlali A et al.

Oncotargets and Therapy, 2017

Methylation of the Vitamin D Receptor (VDR) Gene, Together with Genetic Variation, Race, and Environment Influence the Signaling Efficacy of the Toll-Like Receptor 2/1-VDR Pathway.

Meyer V et al.

Frontiers in Immunology, 2017

Vitamin D status, vitamin D receptor and toll like receptor-2 polymorphisms in tuberculous meningitis: a case-control study.

Rizvi I et al.

Infection, 2016

TLR2 and TLR4 polymorphisms in Southern Chinese Psoriasis Vulgaris patients.

Shi G et al.

Journal of Dermatological Science, 2016

Associations of Toll-Like Receptor and β-Defensin Polymorphisms with Measures of Periodontal Disease (PD) in HIV+ North American Adults: An Exploratory Study.

Mehlotra RK et al.

Plos One, 2016

Effect of smoking on the genetic makeup of toll-like receptors 2 and 6.

Kohailan M et al.

Oncotargets and Therapy, 2016

Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility.

Noreen M et al.

Immunologic Research, 2015

Toll-like receptor polymorphisms and tuberculosis susceptibility: A comprehensive meta-analysis.

Sun Q et al.

Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban, 2015

Association of Single Nucleotide Polymorphisms in Toll-like Receptor Genes With Asthma Risk: A Systematic Review and Meta-analysis.

Tizaoui K et al.

Allergy, Asthma & Immunology Research, 2015

TLR1, 2, 4, 6 and 9 Variants Associated with Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis.

Schurz H et al.

Plos One, 2015

26430737 (PubMed )
Supplement: pone.0139711.s005.xlsx › S1_Table

Genetic polymorphisms of CCL1 rs2072069 G/A and TLR2 rs3804099 T/C in pulmonary or meningeal tuberculosis patients.

Zhao Y et al.

International Journal of Clinical and Experimental Pathology, 2015

Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease.

Bank S et al.

The Pharmacogenomics Journal, 2014

Association of Toll-like receptor polymorphisms with HIV status in North Americans.

Willie B et al.

Genes and Immunity, 2014

Genetic diversity of TLR2, TLR4, and VDR loci and pulmonary tuberculosis in Moroccan patients.

Arji N et al.

Journal of Infection in Developing Countries, 2014

Relevance of single-nucleotide polymorphisms in human TLR genes to infectious and inflammatory diseases and cancer.

Trejo-de la O A et al.

Genes and Immunity, 2014

Role of toll-like receptors gene polymorphism in renal transplantation.

Zhou TB

Journal of Receptor and Signal Transduction Research, 2014

Host genome polymorphisms and tuberculosis infection: What we have to say?

Khalilullah SA et al.

The Egyptian Journal of Chest Diseases and Tuberculosis, 2014

Polymorphisms in toll-like receptors 2, 4 and 5 are associated with Legionella pneumophila infection.

Zhang F et al.

Infection, 2013

A TLR6 polymorphism is associated with increased risk of Legionnaires' disease.

Misch EA et al.

Genes and Immunity, 2013

Toll-like receptor variants are associated with infant HIV-1 acquisition and peak plasma HIV-1 RNA level.

Beima-Sofie KM et al.

Aids (london, England), 2013

The genetics of innate immunity sensors and human disease.

Pothlichet J et al.

International Reviews of Immunology, 2013

Functional polymorphisms of Toll-like receptors 2 and 4 alter the risk for colorectal carcinoma in Europeans.

Pimentel-Nunes P et al.

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2013

Toll-like receptor -1, -2, and -6 polymorphisms and pulmonary tuberculosis susceptibility: a systematic review and meta-analysis.

Zhang Y et al.

Plos One, 2013

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