Varaico: Literature-Extracted Genetic Variants

Gene:TLR2
Variant:p.D299G
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TLR2

NM_001318789.2:p.D299G

Associated Papers

Interaction between toll-like receptor 4 polymorphism and abdominal obesity on ovarian cancer risk in Chinese women.

Zhu J et al.

Bmc Women's Health, 2025

The molecular and histopathological investigations of TLR2 rs5743708 and TLR4 (rs4986790 and rs4986791) polymorphisms effects on cutaneous leishmaniasis lesions.

Feiz-Haddad MH et al.

Experimental Parasitology, 2024

Investigation of TLR2 (-196 to -174del) and TLR9 (T-1486C) Gene Polymorphisms Association with Inflammatory Bowel Diseases.

Emele RE et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2024

A meta-analysis of the association between inflammatory cytokine polymorphism and neonatal sepsis.

Liang J et al.

Plos One, 2024

38848433 (PubMed )
Supplement: pone.0301859.s001.doc

Association between innate immunity gene polymorphisms and neonatal sepsis development: a systematic review and meta-analysis.

Sljivancanin Jakovljevic T et al.

World Journal of Pediatrics : Wjp, 2022

Investigation of TLR2 and TLR4 Polymorphisms and Sepsis Susceptibility: Computational and Experimental Approaches.

Behairy MY et al.

International Journal of Molecular Sciences, 2022

Investigation of Microbial Translocation, TLR and VDR Gene Polymorphisms, and Recurrence Risk in Stage III Colorectal Cancer Patients.

Messaritakis I et al.

Cancers, 2022

Role of innate immune receptors TLR4 and TLR2 polymorphisms in systemic lupus erythematosus susceptibility.

Elloumi N et al.

Annals of Human Genetics, 2022

The Genetic Association Between TLR-1, -2, -4, and -6 Gene Polymorphisms and Rheumatoid Arthritis Susceptibility in a Chinese Han Population.

Peng Y et al.

Genetic Testing and Molecular Biomarkers, 2022

Association of D299G Polymorphism of TLR4 Gene and CagA Virulence Factor of H. pylori among the Iranian Patients with Colorectal Cancer.

Malallah Ghayemi S et al.

Medical Journal of the Islamic Republic of Iran, 2022

Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis.

Heng AHS et al.

Bmc Medical Genomics, 2021

Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis.

Thada S et al.

International Journal of Molecular Sciences, 2021

Toll-like-Receptor Gene Polymorphisms in Tunisian Endemic Pemphigus Foliaceus.

Abida O et al.

Biomed Research International, 2020

Analysis of the Association of Polymorphisms rs5743708 in TLR2 and rs4986790 in TLR4 with Atopic Dermatitis Risk.

Zhang Y et al.

Immunological Investigations, 2019

The Possible Role of Gene Variant Coding Nonfunctional Toll-Like Receptor 2 in the Pathogenesis of Mastocytosis.

Nedoszytko B et al.

International Archives of Allergy and Immunology, 2018

Association of TLR and TREM-1 gene polymorphisms with atherosclerosis severity in a Russian population.

Kutikhin AG et al.

Meta Gene, 2016

TLR2 and TLR4 polymorphisms in Southern Chinese Psoriasis Vulgaris patients.

Shi G et al.

Journal of Dermatological Science, 2016

Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility.

Noreen M et al.

Immunologic Research, 2015

Toll-like receptor 9 promoter polymorphism as a predictive factor of narrow-band UVB phototherapy response in patients with psoriasis.

Romaní J et al.

Photodermatology, Photoimmunology & Photomedicine, 2015

An association between single nucleotide polymorphisms within TLR and TREM-1 genes and infective endocarditis.

Golovkin AS et al.

Cytokine, 2015

Polymorphisms in Toll-like receptor genes are associated with vitiligo.

Traks T et al.

Frontiers in Genetics, 2015

Association of TLR and TREM-1 gene polymorphisms with risk of coronary artery disease in a Russian population.

Golovkin AS et al.

Gene, 2014

The Toll-like receptor 4 polymorphism Asp299Gly but not Thr399Ile influences TLR4 signaling and function.

Long H et al.

Plos One, 2014

Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population.

Torres-García D et al.

Journal of Translational Medicine, 2013

R753Q polymorphism inhibits Toll-like receptor (TLR) 2 tyrosine phosphorylation, dimerization with TLR6, and recruitment of myeloid differentiation primary response protein 88.

Xiong Y et al.

The Journal of Biological Chemistry, 2012

TLR4 polymorphisms and disease susceptibility.

Noreen M et al.

Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.], 2012

Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data.

Baker AR et al.

Plos One, 2012

Genetic variants and the risk for invasive mould disease in immunocompromised hematology patients.

van der Velden WJ et al.

Current Opinion in Infectious Diseases, 2011

Genetic variants of toll-like receptor 2 and 5, helicobacter pylori infection, and risk of gastric cancer and its precursors in a chinese population.

Zeng HM et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2011

Association of polymorphisms in the TLR4 gene with the risk of developing neutropenia in children with leukemia.

Miedema KG et al.

Leukemia, 2011

Genetic variation of TLR-4, TLR-9 and TIRAP genes in Iranian malaria patients.

Zakeri S et al.

Malaria Journal, 2011

Toll-like receptor 2 gene polymorphisms in a Korean population: association with chronic rhinosinusitis.

Park CS et al.

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-head and Neck Surgery, 2011

Expression of TLR-4 and -2 in peripheral mononuclear cells in renal transplant patients with TLR-4 gene polymorphism.

Nogueira E et al.

International Immunopharmacology, 2010

Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma.

Kerkhof M et al.

Thorax, 2010

Very low frequencies of Toll-like receptor 2 supposed-2029T and 2258A (RS5743708) mutant alleles in southern Brazilian critically ill patients: would it be a lack of worldwide-accepted clinical applications of Toll-like receptor 2 variants?

Thurow HS et al.

Genetic Testing and Molecular Biomarkers, 2010

TLR9 polymorphisms are associated with altered IFN-gamma levels in children with cerebral malaria.

Sam-Agudu NA et al.

The American Journal of Tropical Medicine and Hygiene, 2010

Polymorphisms in Toll-like receptor 4 (TLR4) are associated with protection against leprosy.

Bochud PY et al.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 2009

Impact of Toll-like receptors [TLR] 2 (-196 to -174 del) and TLR 4 (Asp299Gly, Thr399Ile) in cervical cancer susceptibility in North Indian women.

Pandey S et al.

Gynecologic Oncology, 2009

A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma.

Purdue MP et al.

Carcinogenesis, 2009

Gene polymorphisms of Toll-like and related recognition receptors in relation to the vaginal carriage of Gardnerella vaginalis and Atopobium vaginae.

Verstraelen H et al.

Journal of Reproductive Immunology, 2009

Association of TLR4-T399I polymorphism with chronic obstructive pulmonary disease in smokers.

Speletas M et al.

Clinical & Developmental Immunology, 2009

Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms in gastric cancer of intestinal and diffuse histotypes.

Santini D et al.

Clinical and Experimental Immunology, 2008

Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease.

Tal G et al.

The Journal of Infectious Diseases, 2004

Clinical characteristics and frequency of TLR4 polymorphisms in Brazilian patients with ankylosing spondylitis.

Machado NP et al.

Revista Brasileira De Reumatologia, 0

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