Varaico: Literature-Extracted Genetic Variants

Gene:TLR2
Variant:p.S450S
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TLR2

NM_001318789.2:p.S450S

Associated Papers

Pharmacokinetic and neuroimmune pharmacogenetic impacts on slow-release morphine cancer pain control and adverse effects.

Barratt DT et al.

The Pharmacogenomics Journal, 2024

38824169 (PubMed )
Supplement: 41397_2024_339_MOESM3_ESM.pdf

Polymorphisms in Immune Genes and Their Association with Tuberculosis Susceptibility: An Analysis of the African Population.

Wodelo W et al.

The Application of Clinical Genetics, 2024

Genetic Risk Factors for Nontuberculous Mycobacterial Pulmonary Disease (Systematic Review).

Sviridov PS et al.

Sovremennye Tekhnologii V Meditsine, 2024

Analysis of Epidemiological Factors and SNP rs3804100 of TLR2 for COVID-19 in a Cohort of Professionals Who Worked in the First Pandemic Wave in Belém-PA, Brazil.

Silva MJA et al.

Genes, 2023

Relevance of Coding Variation in FLG And DOCK8 in Finnish Pediatric Patients with Early-Onset Moderate-To-Severe Atopic Dermatitis.

Perälä M et al.

Jid Innovations : Skin Science From Molecules to Population Health, 2023

37533579 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_S1

-196 to -174del, rs4696480, rs3804099 polymorphisms of Toll-like receptor 2 gene impact the susceptibility of cancers: evidence from 37053 subjects.

Gao SL et al.

Bioscience Reports, 2019

Toll-like receptor polymorphism in host immune response to infectious diseases: A review.

Mukherjee S et al.

Scandinavian Journal of Immunology, 2019

Host Genetics of Cytomegalovirus Pathogenesis.

Sezgin E et al.

Frontiers in Genetics, 2019

No Major Effect of Innate Immune Genetics on Acute Kidney Rejection in the First 2 Weeks Post-Transplantation.

Hu R et al.

Frontiers in Pharmacology, 2019

Potential role of Toll-like receptor 2 expression and polymorphisms in colon cancer susceptibility in the Saudi Arabian population.

Semlali A et al.

Oncotargets and Therapy, 2018

Toll-like receptors genes polymorphisms and the occurrence of HCMV infection among pregnant women.

Wujcicka W et al.

Virology Journal, 2017

TLR2 2258 G>A single nucleotide polymorphism and the risk of congenital infection with human cytomegalovirus.

Wujcicka W et al.

Virology Journal, 2017

No genetic relationship between TLR2 rs4696480, rs3804100, and rs3804099 gene polymorphisms and female breast cancer in Saudi populations.

Semlali A et al.

Oncotargets and Therapy, 2017

Ethnicity-dependent influence of innate immune genetic markers on morphine PCA requirements and adverse effects in postoperative pain.

Somogyi AA et al.

Pain, 2016

Toll-like receptor 2 gene polymorphisms in Korean women with human papillomavirus-related cervical neoplasia.

Kim JH et al.

Acta Obstetricia Et Gynecologica Scandinavica, 2016

TLR9 -1486T/C and 2848C/T SNPs Are Associated with Human Cytomegalovirus Infection in Infants.

Paradowska E et al.

Plos One, 2016

Effect of smoking on the genetic makeup of toll-like receptors 2 and 6.

Kohailan M et al.

Oncotargets and Therapy, 2016

TLR2, TLR4 and CD86 gene polymorphisms in recurrent aphthous stomatitis.

Karasneh J et al.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2015

Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility.

Noreen M et al.

Immunologic Research, 2015

Predictive model for risk of severe gastrointestinal toxicity following chemotherapy using patient immune genetics and type of cancer: a pilot study.

Coller JK et al.

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer, 2015

Toll-like receptor polymorphisms and tuberculosis susceptibility: A comprehensive meta-analysis.

Sun Q et al.

Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban, 2015

Association of Single Nucleotide Polymorphisms in Toll-like Receptor Genes With Asthma Risk: A Systematic Review and Meta-analysis.

Tizaoui K et al.

Allergy, Asthma & Immunology Research, 2015

Association of Toll-like receptor polymorphisms with HIV status in North Americans.

Willie B et al.

Genes and Immunity, 2014

Toll-like receptor 2 and 9 genetic polymorphisms and the susceptibility to B cell Non-Hodgkin Lymphoma in Egypt.

Rahman HA et al.

Annals of Hematology, 2014

A TLR6 polymorphism is associated with increased risk of Legionnaires' disease.

Misch EA et al.

Genes and Immunity, 2013

Toll-like receptor variants are associated with infant HIV-1 acquisition and peak plasma HIV-1 RNA level.

Beima-Sofie KM et al.

Aids (london, England), 2013

SNPs in toll-like receptor (TLR) genes as new genetic alterations associated with congenital toxoplasmosis?

Wujcicka W et al.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 2013

The genetics of innate immunity sensors and human disease.

Pothlichet J et al.

International Reviews of Immunology, 2013

Toll-like receptor -1, -2, and -6 polymorphisms and pulmonary tuberculosis susceptibility: a systematic review and meta-analysis.

Zhang Y et al.

Plos One, 2013

Association of Toll-like receptor 2 polymorphisms with papillary thyroid cancer and clinicopathologic features in a Korean population.

Kim MK et al.

Journal of Korean Medical Science, 2012

Association studies of gene polymorphisms in toll-like receptors 2 and 4 in Croatian patients with acute myocardial infarction.

Džumhur A et al.

Scandinavian Journal of Immunology, 2012

Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data.

Baker AR et al.

Plos One, 2012

Leprosy and the human genome.

Misch EA et al.

Microbiology and Molecular Biology Reviews : Mmbr, 2010

No associations of Toll-like receptor 2 (TLR2) -196 to -174del polymorphism with the risk of Helicobacter pylori seropositivity, gastric atrophy, and gastric cancer in Japanese.

Hishida A et al.

Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2010

Association between Toll-like receptor 2 (TLR2) polymorphisms and asymptomatic bancroftian filariasis.

Junpee A et al.

Parasitology Research, 2010

Toll-like receptor 2 (P631H) mutant impairs membrane internalization and is a dominant negative allele.

Etokebe GE et al.

Scandinavian Journal of Immunology, 2010

Identification of polymorphisms in the Toll-like receptor gene and the association with allergic rhinitis.

Kang I et al.

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-rhino-laryngological Societies (eufos) : Affiliated With the German Society for Oto-rhino-laryngology - Head and Neck Surgery, 2010

Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts.

Chen YC et al.

Bmc Medical Genetics, 2010

[Gene polymorphisms of Toll-like receptors in Chinese Han children with sepsis in Wenzhou].

Shan XO et al.

Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics, 2010

Single-nucleotide polymorphisms in genes encoding toll-like receptor -2, -3, -4, and -9 in case-control study with breast cancer.

Etokebe GE et al.

Genetic Testing and Molecular Biomarkers, 2009

Gene polymorphisms of Toll-like and related recognition receptors in relation to the vaginal carriage of Gardnerella vaginalis and Atopobium vaginae.

Verstraelen H et al.

Journal of Reproductive Immunology, 2009

Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy.

Bochud PY et al.

The Journal of Infectious Diseases, 2008

Polymorphisms in TLR2 are associated with increased viral shedding and lesional rate in patients with genital herpes simplex virus Type 2 infection.

Bochud PY et al.

The Journal of Infectious Diseases, 2007

A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis.

Thuong NT et al.

Genes and Immunity, 2007

Characterization and investigation of single nucleotide polymorphisms and a novel TLR2 mutation in the human TLR2 gene.

Merx S et al.

Human Molecular Genetics, 2007

No association of TLR2 and TLR4 polymorphisms with type I diabetes mellitus in the Basque population.

Santin I et al.

Annals of the New York Academy of Sciences, 2006

Association of the polymorphism for Toll-like receptor 2 with type 1 diabetes susceptibility.

Park Y et al.

Annals of the New York Academy of Sciences, 2004

An association study of asthma and total serum immunoglobin E levels for Toll-like receptor polymorphisms in a Japanese population.

Noguchi E et al.

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology, 2004

A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection.

Lorenz E et al.

Infection and Immunity, 2000

[Association of polymorphisms in toll-like receptor genes with atopic dermatitis in the Republic of Bashkortostan].

Gimalova GF et al.

Molekuliarnaia Biologiia, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."