Varaico: Literature-Extracted Genetic Variants

Gene:TLR2
Variant:p.R677W
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TLR2

NM_001318789.2:p.R677W

Associated Papers

The association between toll-like receptor gene polymorphism and Helicobacter pylori infection risk: A systematic review and meta-analysis.

Xu Z et al.

Medicine, 2026

The effect of inflammatory factors on unstable angina risk, from the gene level.

Lou J et al.

Scientific Reports, 2026

Toll-like receptor 3 (TLR 3) polymorphisms predisposition to schizophrenia and bipolar disorder.

Aflouk Y et al.

Molecular Biology Reports, 2025

The Role of TLR2/TLR4 Receptors in Host Genetic Susceptibility to Recurrent Vulvovaginitis.

Routsias J et al.

Journal of Fungi (basel, Switzerland), 2025

The evolutionary landscape of host immunity genes involved in respiratory and other immune-related diseases, and their association with severe COVID-19 outcomes.

Cross CN et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

Genetic Predisposition of TLR 1 and TLR 6 Polymorphisms to Schizophrenia Onset and Prediction of Treatment Response.

Aflouk Y et al.

Biochemical Genetics, 2025

The molecular and histopathological investigations of TLR2 rs5743708 and TLR4 (rs4986790 and rs4986791) polymorphisms effects on cutaneous leishmaniasis lesions.

Feiz-Haddad MH et al.

Experimental Parasitology, 2024

Investigation of TLR2 (-196 to -174del) and TLR9 (T-1486C) Gene Polymorphisms Association with Inflammatory Bowel Diseases.

Emele RE et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2024

Polymorphisms in Immune Genes and Their Association with Tuberculosis Susceptibility: An Analysis of the African Population.

Wodelo W et al.

The Application of Clinical Genetics, 2024

Genetic Variation in Toll-Like Receptors (TLRs) 2, 4, and 9 Influences HIV Disease Progression Toward Active TB and AIDS.

Kaushik G et al.

Journal of Inflammation Research, 2024

Quantitative assessment of the association between TNF-α gene polymorphisms and angina risk.

Xu S et al.

American Journal of Translational Research, 2024

Human Toll-like receptor 2 genetic polymorphisms with tuberculosis susceptibility: A systematic review and meta-analysis.

Chen R et al.

Cytokine, 2023

Association between polymorphisms of TLR2-1-6 and bipolar disorder in a tunisian population.

Aflouk Y et al.

Molecular Biology Reports, 2023

Single Nucleotide Variants in the TLR1, TLR2 and TLR6 Genes: A Case-Control Study in a Colombian Population.

Gutierrez-Castañeda LD et al.

Tropical Medicine and Infectious Disease, 2023

Comparative Genetic Association Analysis of Human Genetic Susceptibility to Pulmonary and Lymph Node Tuberculosis.

Abhimanyu et al.

Genes, 2023

Toll-like receptor-2 (TLR-2) rs111200466 variant offers protection against SARS-CoV-2 infections and mortality: a worldwide epidemiological correlation analysis.

Nayak N et al.

Nucleosides, Nucleotides & Nucleic Acids, 2023

Systematic review and meta-analysis of human Toll-like receptors genetic polymorphisms for susceptibility to tuberculosis infection.

Varshney D et al.

Cytokine, 2022

Genetic polymorphisms of toll-like receptors in leprosy patients from southern Brazil.

Masin PS et al.

Frontiers in Genetics, 2022

Association between TLR2 polymorphisms (- 196-174 Ins/Del, R677W, R753Q, and P631H) and schizophrenia in a Tunisian population.

Aflouk Y et al.

Immunologic Research, 2021

The current role of NLRP3 inflammasome polymorphism in gout susceptibility.

Clavijo-Cornejo D et al.

International Journal of Rheumatic Diseases, 2021

Genetic polymorphisms as multi-biomarkers in severe acute respiratory syndrome (SARS) by coronavirus infection: A systematic review of candidate gene association studies.

Dos Santos ACM et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2021

Toll-Like Receptor Signaling in the Establishment and Function of the Immune System.

Aluri J et al.

Cells, 2021

Toll-like receptor gene polymorphisms in patients with myeloproliferative neoplasms.

Quirino MG et al.

Molecular Biology Reports, 2021

Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis.

Heng AHS et al.

Bmc Medical Genomics, 2021

Single Nucleotide Polymorphisms in the Bovine TLR2 Extracellular Domain Contribute to Breed and Species-Specific Innate Immune Functionality.

Bartens MC et al.

Frontiers in Immunology, 2021

Genotype Frequency of the Common TLR4 SNPs in a Kurdish Population: Global Reviews and Out-of-African Migrations.

Niranji SS et al.

Human Biology, 2021

Association of toll-like receptor polymorphisms with acquisition of HIV infection and clinical findings: A protocol for systematic review and meta-analysis.

Shi H et al.

Medicine, 2020

The Arg753Gln Polymorphism of Toll-Like Receptor 2 Has a Lower Occurrence in Patients with Syphilis, Suggesting Its Protective Effect in Czech and Slovak Individuals.

Grillová L et al.

Infection and Immunity, 2020

Variants in taste genes on caries risk and caries activity status.

Yıldız Telatar G et al.

Medical Molecular Morphology, 2020

TLR4 896A/G and TLR9 1174G/A polymorphisms are associated with the risk of infectious mononucleosis.

Jabłońska A et al.

Scientific Reports, 2020

Association between TLR2 Arg677Trp polymorphism and tuberculosis susceptibility: A meta-analysis.

Jin X et al.

Microbial Pathogenesis, 2020

TLR2 2029C/T and TLR3 1377C/T and -7C/A Polymorphisms Are Associated with the Occurrence of Abdominal Aortic Aneurysm.

Jabłońska A et al.

Journal of Immunology (baltimore, Md. : 1950), 2020

Homoplastic single nucleotide polymorphisms contributed to phenotypic diversity in Mycobacterium tuberculosis.

Tantivitayakul P et al.

Scientific Reports, 2020

Toll-like receptor 2 polymorphisms and their effect on the immune response to ESAT-6, Pam3CSK4 TLR2 agonist in pulmonary tuberculosis patients and household contacts.

Mandala JP et al.

Cytokine, 2020

Higher Levels of Serum TLR2 and TLR4 in Patients with Hashimoto's Thyroiditis.

Aktaş T et al.

Endocrine, Metabolic & Immune Disorders Drug Targets, 2020

Toll-like-Receptor Gene Polymorphisms in Tunisian Endemic Pemphigus Foliaceus.

Abida O et al.

Biomed Research International, 2020

Toll-like receptor polymorphism in host immune response to infectious diseases: A review.

Mukherjee S et al.

Scandinavian Journal of Immunology, 2019

Host genetic variants in sepsis risk: a field synopsis and meta-analysis.

Lu H et al.

Critical Care (london, England), 2019

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Host Genetics of Cytomegalovirus Pathogenesis.

Sezgin E et al.

Frontiers in Genetics, 2019

Human Genetic Variation and HIV/AIDS in Papua New Guinea: Time to Connect the Dots.

Mehlotra RK

Current Hiv/aids Reports, 2018

Association of VDR gene polymorphisms and 22 bp deletions in the promoter region of TLR2Δ22 (-196-174) with increased risk of pulmonary tuberculosis: A case-control study in tea garden communities of Assam.

Devi KR et al.

Journal of Clinical Laboratory Analysis, 2018

Influence of polymorphisms in toll-like receptors (TLRs) on malaria susceptibility in low-endemic area of the Atlantic Forest, São Paulo, Brazil.

Guimarães LO et al.

Acta Tropica, 2018

Arg753gln and Arg677 Trp Polymorphisms of Toll-Like Receptor 2 In Acute Apical Abscess.

Miri-Moghaddam E et al.

Journal of Dentistry (shiraz, Iran), 2018

Genetically defined variants of toll-like receptors 3, 7 and 9 as phenotype and risk modifier factors for psoriasis.

Julià M et al.

Journal of Dermatological Science, 2018

Predilection to Dermato-Lymphangio-Adenitis in Obstructive Lymphedema of Lower Limbs Depending on Genetic Polymorphisms at TNFα-308G>A, CCR2-190G>A, CD14-159C>T, TLR2 2029C>T, TLR4 1063A>G, TLR4 1363C>T, TGFβ 74G>C, and TGFβ 29T>C.

Olszewski WL et al.

Lymphatic Research and Biology, 2018

Genetic ancestry effects on the distribution of toll-like receptors (TLRs) gene polymorphisms in a population of the Atlantic Forest, São Paulo, Brazil.

Guimarães LO et al.

Human Immunology, 2018

TLR2 Arg677Trp but not TLR2 -196 to -174 ins/del and Arg753Gln polymorphism alter the risk of peptic ulcer in north of Iran.

Habibzadeh M et al.

Journal of the Chinese Medical Association : Jcma, 2018

Association Between Arg753Gln and Arg677Trp Polymorphisms of TLR2 Gene with Active Pulmonary Tuberculosis in an Indonesian Population.

Soeroto AY et al.

Acta Medica Indonesiana, 2018

Susceptibility to HIV-1 infection is influenced by toll like receptor-2 (-196 to -174) polymorphism in a north Indian population.

Vidyant S et al.

The Journal of Gene Medicine, 2017

The R753Q polymorphism in Toll-like receptor 2 (TLR2) attenuates innate immune responses to mycobacteria and impairs MyD88 adapter recruitment to TLR2.

Pattabiraman G et al.

The Journal of Biological Chemistry, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."