Varaico: Literature-Extracted Genetic Variants

Gene:TLR2
Variant:p.P681A
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TLR2

NM_001318789.2:p.P681A

Associated Papers

Expression of Concern: Divergent Roles of Amino Acid Residues Inside and Outside the BB Loop Affect Human Toll-Like Receptor (TLR)2/2, TLR2/1 and TLR2/6 Responsiveness.

Unknown Author

Plos One, 2024

An alanine-to-proline mutation in the BB-loop of TLR3 Toll/IL-1R domain switches signalling adaptor specificity from TRIF to MyD88.

Verstak B et al.

Journal of Immunology (baltimore, Md. : 1950), 2013

Divergent roles of amino acid residues inside and outside the BB loop affect human Toll-like receptor (TLR)2/2, TLR2/1 and TLR2/6 responsiveness.

Qiu Y et al.

Plos One, 2013

Binding specificity of Toll-like receptor cytoplasmic domains.

Brown V et al.

European Journal of Immunology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."