Varaico: Literature-Extracted Genetic Variants

Gene:TLR2
Variant:p.R753Q
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TLR2

NM_001318789.2:p.R753Q

Associated Papers

IFNAR2 p.F8S Variant Associates with Severe COVID-19 and Adaptive Immune Cell Activation Modulation.

Malvestiti F et al.

International Journal of Molecular Sciences, 2026

41596638 (PubMed )
Supplement: ijms-27-00992-s001.zip › Malvestiti_et_al.__Supplementary_Table__y.xlsx › Table_S1

Exploratory Analysis of TLR2, TLR4, Interleukin 6 and Interleukin 10 Gene Polymorphisms in Relation to Clinical Early-Onset Sepsis in Preterm Neonates: A Single-Center Study.

Baizat M et al.

Life (basel, Switzerland), 2026

Genetics of childhood tuberculosis: A scoping review.

Pinheiro Mascarenhas MA et al.

Paediatric Respiratory Reviews, 2025

Toll-like receptor 3 (TLR 3) polymorphisms predisposition to schizophrenia and bipolar disorder.

Aflouk Y et al.

Molecular Biology Reports, 2025

The Role of TLR2/TLR4 Receptors in Host Genetic Susceptibility to Recurrent Vulvovaginitis.

Routsias J et al.

Journal of Fungi (basel, Switzerland), 2025

Association of Toll-like receptor 3 rs3775291 with Zika virus infection in Brazil.

Ayo CM et al.

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2025

The evolutionary landscape of host immunity genes involved in respiratory and other immune-related diseases, and their association with severe COVID-19 outcomes.

Cross CN et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

Impact of Sociodemographic, Clinical, and Genetic Factors and Fusobacterium nucleatum on Premature Birth Outcomes in Women from Kazakhstan: A Case-Control Study.

Zhurabekova G et al.

Iranian Journal of Medical Sciences, 2025

Potential impact of micro-196a2 and Toll-like receptor 2 gene polymorphisms on oral cancer prognosis and susceptibility.

Simonovic M et al.

Archives of Oral Biology, 2025

Genetic Regulation of Immune Response in Dogs.

Barragán-Sánchez P et al.

Genes, 2025

Genetic Predisposition of TLR 1 and TLR 6 Polymorphisms to Schizophrenia Onset and Prediction of Treatment Response.

Aflouk Y et al.

Biochemical Genetics, 2025

Host Genetic Factors in Q Fever Susceptibility.

Robaina Bordón JM et al.

Pathogens (basel, Switzerland), 2025

Features of toll-like receptor genes (TLR-2, TLR-3, TLR-4 and TLR-6) polymorphism in open-angle glaucoma patients.

Shevchenko AV et al.

Vavilovskii Zhurnal Genetiki I Selektsii, 2025

Serum levels of Wnt5a in Egyptian women with obesity and their association with toll like receptor 2 Arg753Gln gene polymorphism in a pilot case control study of obesity as a state of metaflammation.

Fouad SH et al.

Scientific Reports, 2025

Association between TLR-2 and TLR-9 gene polymorphisms (rs5743708 and rs5743836) and susceptibility to psoriatic arthritis in Egyptian patients.

Abdelbaset NE et al.

The Egyptian Journal of Immunology, 2025

Genomic Insights into Host Susceptibility to Periprosthetic Joint Infections: A Comprehensive Literature Review.

Lizcano JD et al.

Microorganisms, 2024

The molecular and histopathological investigations of TLR2 rs5743708 and TLR4 (rs4986790 and rs4986791) polymorphisms effects on cutaneous leishmaniasis lesions.

Feiz-Haddad MH et al.

Experimental Parasitology, 2024

Vitiligo: From mechanisms of disease to treatable pathways.

Pathak GN et al.

Skin Health and Disease, 2024

Exome Sequencing of a Blastomycosis Case-Control Cohort From Manitoba and Northwestern Ontario, Canada.

Jankowski P et al.

Mycoses, 2024

Genetic polymorphisms of TLR1, TLR2, TLR3 and TLR4 in patients with recurrent or severe infections.

Teräsjärvi J et al.

International Journal of Immunogenetics, 2024

Validating genetic variants in innate immunity linked to infectious events in acute myeloid leukemia post-induction chemotherapy.

Schnetzke U et al.

Genes and Immunity, 2024

Impact of Toll-like receptor 2 (rs5743708) gene polymorphism in pediatric pneumonia: risk and severity.

Abd El-Hamid SM et al.

The Egyptian Journal of Immunology, 2024

Association between polymorphisms and atopic dermatitis susceptibility: A systematic review and meta-analysis.

Huang Y et al.

Gene, 2024

TLR2 and TLR4 Polymorphisms Are Not Associated with Dental Caries in Polish Children.

Milona M et al.

International Journal of Molecular Sciences, 2024

Investigation of TLR2 (-196 to -174del) and TLR9 (T-1486C) Gene Polymorphisms Association with Inflammatory Bowel Diseases.

Emele RE et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2024

SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease.

Strausz S et al.

Nature Communications, 2024

38503741 (PubMed )
Supplement: 41467_2024_45983_MOESM2_ESM.pdf

Polymorphisms in Immune Genes and Their Association with Tuberculosis Susceptibility: An Analysis of the African Population.

Wodelo W et al.

The Application of Clinical Genetics, 2024

Human Toll-like receptor 2 genetic polymorphisms with tuberculosis susceptibility: A systematic review and meta-analysis.

Chen R et al.

Cytokine, 2023

The human Toll-like receptor 2 (TLR2) response during pathogenic Leptospira infection.

Kappagoda CN et al.

Biorxiv : the Preprint Server for Biology, 2023

Association between polymorphisms of TLR2-1-6 and bipolar disorder in a tunisian population.

Aflouk Y et al.

Molecular Biology Reports, 2023

Single Nucleotide Variants in the TLR1, TLR2 and TLR6 Genes: A Case-Control Study in a Colombian Population.

Gutierrez-Castañeda LD et al.

Tropical Medicine and Infectious Disease, 2023

Evaluation of the Impact of Some Single-Nucleotide Gene Polymorphisms on the Development of Adenomatous Polyps of the Colon in Patients with Irritable Bowel Syndrome.

Kyrian O et al.

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology, 2023

Candidate Gene Association Studies in Atopic Dermatitis in Participants of European and Asian Ancestry: A Systematic Review and Meta-Analysis.

Pontikas A et al.

Genes, 2023

A study on the immunological vitality of an inflammatory biomarker explored with rs5743708 polymorphism in TLR2 gene among Saudi women confirmed with polycystic ovarian syndrome.

Alshammary AF et al.

Saudi Journal of Biological Sciences, 2023

Relevance of Coding Variation in FLG And DOCK8 in Finnish Pediatric Patients with Early-Onset Moderate-To-Severe Atopic Dermatitis.

Perälä M et al.

Jid Innovations : Skin Science From Molecules to Population Health, 2023

37533579 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_S1

Association of Toll-like receptor 2 rs111200466 polymorphism with low serum levels of IL-33 in early childhood.

Teräsjärvi JT et al.

Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, 2023

A narrative review of precision medicine in neonatal sepsis: genetic and epigenetic factors associated with disease susceptibility.

Dai W et al.

Translational Pediatrics, 2023

Toll-like receptor 2-mediated downstream cytokine levels as determinant of malaria pathogenesis.

Kalita MP et al.

The Indian Journal of Medical Research, 2023

Potential Impact of Polymorphisms in Toll-like Receptors 2, 3, 4, 7, 9, miR-146a, miR-155, and miR-196a Genes on Osteoarthritis Susceptibility.

Stefik D et al.

Biology, 2023

Association of TLR2 and TLR9 gene polymorphisms with atopic dermatitis: a systematic review and meta-analysis with trial sequential analysis.

Zhou B et al.

Immunological Medicine, 2023

Toll-like receptor-2 (TLR-2) rs111200466 variant offers protection against SARS-CoV-2 infections and mortality: a worldwide epidemiological correlation analysis.

Nayak N et al.

Nucleosides, Nucleotides & Nucleic Acids, 2023

Impact of Toll-Like Receptor 2 and 9 Gene Polymorphisms on COVID-19: Susceptibility, Severity, and Thrombosis.

Alhabibi AM et al.

Journal of Inflammation Research, 2023

Myeloid lineage cells evince distinct steady-state level of certain gene groups in dependence on hereditary angioedema severity.

Ballonová L et al.

Frontiers in Genetics, 2023

37470035 (PubMed )
Supplement: Table1.XLSX › Table_S3_Deleterious_gene_varia

Genetic Variants Associated with Acne Vulgaris.

Zhang H et al.

International Journal of General Medicine, 2023

Evaluation of toll-like receptors 2 and 4 polymorphism and intestinal microbiota in children with food allergies.

Kılıç M et al.

The Turkish Journal of Pediatrics, 2023

TLRs Gene Polymorphisms Associated with Pneumonia before and during COVID-19 Pandemic.

Salamaikina S et al.

Diagnostics (basel, Switzerland), 2022

Investigation of TLR2 and TLR4 Polymorphisms and Sepsis Susceptibility: Computational and Experimental Approaches.

Behairy MY et al.

International Journal of Molecular Sciences, 2022

Psoriasis: An Immunogenetic Perspective.

Kocaaga A et al.

Global Medical Genetics, 2022

Role of innate immune receptors TLR4 and TLR2 polymorphisms in systemic lupus erythematosus susceptibility.

Elloumi N et al.

Annals of Human Genetics, 2022

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."