Varaico: Literature-Extracted Genetic Variants

Gene:TLR3
Variant:p.N284I
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TLR3

NM_003265.3:p.N284I

Associated Papers

"In silico analysis of human TLR3 missense single nucleotide polymorphisms and their potential association with cancer".

Agarwal M et al.

Scientific Reports, 2025

Severe influenza pneumonitis in children with inherited TLR3 deficiency.

Lim HK et al.

The Journal of Experimental Medicine, 2019

31217193 (PubMed )
Supplement: JEM_20181621_sm.pdf

Toll-like receptor polymorphism in host immune response to infectious diseases: A review.

Mukherjee S et al.

Scandinavian Journal of Immunology, 2019

Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children.

Studzińska M et al.

Plos One, 2017

Characterization of Disease-Associated Mutations in Human Transmembrane Proteins.

Molnár J et al.

Plos One, 2016

26986070 (PubMed )
Supplement: pone.0151760.s001.xlsx › polymorphism

A Bioinformatics Approach to Prioritize Single Nucleotide Polymorphisms in TLRs Signaling Pathway Genes.

Alipoor B et al.

International Journal of Molecular and Cellular Medicine, 2016

Toll-like receptor-3 gene polymorphism in patients with Japanese encephalitis.

Biyani S et al.

Journal of Neuroimmunology, 2015

Mutations in toll-like receptor 3 are associated with elevated levels of rotavirus-specific IgG antibodies in IgA-deficient but not IgA-sufficient individuals.

Günaydın G et al.

Clinical and Vaccine Immunology : Cvi, 2014

Insights into the European rabbit (Oryctolagus cuniculus) innate immune system: genetic diversity of the toll-like receptor 3 (TLR3) in wild populations and domestic breeds.

Abrantes J et al.

Bmc Genetics, 2013

Association of Toll-like receptor 3 polymorphisms with chronic hepatitis B and hepatitis B-related acute-on-chronic liver failure.

Rong Y et al.

Inflammation, 2013

Association between a functional polymorphism in Toll-like receptor 3 and chronic hepatitis C in liver transplant recipients.

Lee SO et al.

Transplant Infectious Disease : an Official Journal of the Transplantation Society, 2013

Toll-like receptors and human disease: lessons from single nucleotide polymorphisms.

Lin YT et al.

Current Genomics, 2012

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity.

Guo Y et al.

The Journal of Experimental Medicine, 2011

A real-time PCR assay for the simultaneous detection of functional N284I and L412F polymorphisms in the human Toll-like receptor 3 gene.

Brown RA et al.

The Journal of Molecular Diagnostics : Jmd, 2010

Toll-like receptor 3 immune deficiency may be causative for HSV-2-associated mollaret meningitis.

Willmann O et al.

European Neurology, 2010

Pyrosequencing of toll-like receptor polymorphisms of functional relevance.

Ahmad-Nejad P

Methods in Molecular Biology (clifton, N.j.), 2009

Toll-like receptor polymorphisms and susceptibility to human disease.

Misch EA et al.

Clinical Science (london, England : 1979), 2008

Effects of single nucleotide polymorphisms on Toll-like receptor 3 activity and expression in cultured cells.

Ranjith-Kumar CT et al.

The Journal of Biological Chemistry, 2007

Polymorphisms in Toll-like receptor 9 influence the clinical course of HIV-1 infection.

Bochud PY et al.

Aids (london, England), 2007

Toll-like receptor 3 acts as a suppressor gene in breast cancer initiation and progression: a two-stage association study and functional investigation.

Fan L et al.

Oncoimmunology, 0

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