Varaico: Literature-Extracted Genetic Variants

Gene:TLR3
Variant:p.G743D
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TLR3

NM_003265.3:p.G743D

Associated Papers

"In silico analysis of human TLR3 missense single nucleotide polymorphisms and their potential association with cancer".

Agarwal M et al.

Scientific Reports, 2025

Concomitant Ultrarare Mutations in TLR3 and CTPS2 in a Patient with Severe and Recurrent Respiratory Infections in Early Life.

Bougarn S et al.

Journal of Clinical Immunology, 2024

Inborn Errors of Immunity Predisposing to Herpes Simplex Virus Infections of the Central Nervous System.

Skouboe MK et al.

Pathogens (basel, Switzerland), 2023

Multiple genetic variants involved in both autoimmunity and autoinflammation detected in Chinese patients with sporadic Meniere's disease: a preliminary study.

Zou J et al.

Frontiers in Neurology, 2023

Life-Threatening Enterovirus 71 Encephalitis in Unrelated Children with Autosomal Dominant TLR3 Deficiency.

Kuo CY et al.

Journal of Clinical Immunology, 2022

Inborn errors of TLR3- or MDA5-dependent type I IFN immunity in children with enterovirus rhombencephalitis.

Chen J et al.

The Journal of Experimental Medicine, 2021

The role of host genetics in susceptibility to severe viral infections in humans and insights into host genetics of severe COVID-19: A systematic review.

Elhabyan A et al.

Virus Research, 2020

Heterozygous TLR3 Mutation in Patients with Hantavirus Encephalitis.

Partanen T et al.

Journal of Clinical Immunology, 2020

Severe influenza pneumonitis in children with inherited TLR3 deficiency.

Lim HK et al.

The Journal of Experimental Medicine, 2019

Identification and characterization of rare toll-like receptor 3 variants in patients with autoimmune Addison's disease.

Aslaksen S et al.

Journal of Translational Autoimmunity, 2019

TLR3 Mutations in Adult Patients With Herpes Simplex Virus and Varicella-Zoster Virus Encephalitis.

Sironi M et al.

The Journal of Infectious Diseases, 2017

TLR3 deficiency in herpes simplex encephalitis: high allelic heterogeneity and recurrence risk.

Lim HK et al.

Neurology, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."