Varaico: Literature-Extracted Genetic Variants

Gene:TLR3
Variant:p.W769*
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TLR3

NM_003265.3:p.W769*

Associated Papers

Modelling severe COVID-19 in TLR3-mutated hiPSCs-derived lung organoids.

Latini A et al.

Cell Death Discovery, 2025

Concomitant Ultrarare Mutations in TLR3 and CTPS2 in a Patient with Severe and Recurrent Respiratory Infections in Early Life.

Bougarn S et al.

Journal of Clinical Immunology, 2024

39312089 (PubMed )
Supplement: 10875_2024_1804_MOESM1_ESM.docx

The association of COVID-19 severity and susceptibility and genetic risk factors: A systematic review of the literature.

Ishak A et al.

Gene, 2022

Life-Threatening Enterovirus 71 Encephalitis in Unrelated Children with Autosomal Dominant TLR3 Deficiency.

Kuo CY et al.

Journal of Clinical Immunology, 2022

An overview of human proteins and genes involved in SARS-CoV-2 infection.

Jahanafrooz Z et al.

Gene, 2022

Human genetic basis of severe or critical illness in COVID-19.

Ji XS et al.

Frontiers in Cellular and Infection Microbiology, 2022

Inborn errors of TLR3- or MDA5-dependent type I IFN immunity in children with enterovirus rhombencephalitis.

Chen J et al.

The Journal of Experimental Medicine, 2021

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.

Zhang Q et al.

Science (new York, N.y.), 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."