Associated Papers
"In silico analysis of human TLR3 missense single nucleotide polymorphisms and their potential association with cancer".
Agarwal M et al.
Scientific Reports, 2025
Structural insights into the role of deleterious mutations at the dimeric interface of Toll-like receptor interferon-β related adaptor protein.
Verma S et al.
Proteins, 2024
Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons.
Ritchie L et al.
Neuropharmacology, 2018
Probing subtle conformational changes induced by phosphorylation and point mutations in the TIR domains of TLR2 and TLR3.
Mahita J et al.
Proteins, 2018
Investigating the effect of key mutations on the conformational dynamics of toll-like receptor dimers through molecular dynamics simulations and protein structure networks.
Mahita J et al.
Proteins, 2018
Reconstructing the TIR Side of the Myddosome: a Paradigm for TIR-TIR Interactions.
Vyncke L et al.
Structure (london, England : 1993), 2016
An alanine-to-proline mutation in the BB-loop of TLR3 Toll/IL-1R domain switches signalling adaptor specificity from TRIF to MyD88.
Verstak B et al.
Journal of Immunology (baltimore, Md. : 1950), 2013
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