Varaico: Literature-Extracted Genetic Variants

Gene:TLR4
Variant:p.T399I
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TLR4

NM_138554.5:p.T399I

Associated Papers

From Bench to Bedside: Personalized Genomics in the Diagnosis and Treatment of Osteomyelitis.

Hoveidaei AH et al.

Antibiotics (basel, Switzerland), 2026

Analysis of TNFAIP3, IRAK1, and TLR4 Gene Polymorphisms in Patients With Rheumatoid Arthritis.

Tang Z et al.

Immunity, Inflammation and Disease, 2026

Protective Association of TLR6 rs5743810 with Pulmonary Tuberculosis in the Population of JAMMU Region.

Sharma S et al.

Indian Journal of Microbiology, 2026

Host genetic factors modulating dengue virus: a systematic review of TLR polymorphisms.

Candrasari DS et al.

Bmc Infectious Diseases, 2026

Polymorphisms in TLR4 and IL6 and their association with obesity and insulin resistance in a Venezuelan population.

Hernández Osorio S et al.

Endocrinologia, Diabetes Y Nutricion, 2026

Genetic polymorphisms and diabetic foot ulcer susceptibility: a systematic review and meta-analysis of Indian populations.

Kumar YS et al.

Journal of Diabetes and Metabolic Disorders, 2025

Toll-like receptor 3 (TLR 3) polymorphisms predisposition to schizophrenia and bipolar disorder.

Aflouk Y et al.

Molecular Biology Reports, 2025

The Role of TLR2/TLR4 Receptors in Host Genetic Susceptibility to Recurrent Vulvovaginitis.

Routsias J et al.

Journal of Fungi (basel, Switzerland), 2025

Genetic markers at the crossroads: toll-like receptor polymorphisms and Plasmodium vivax malaria parasitological aspects from the Brazil-French Guiana border.

Cerilo-Filho M et al.

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2025

Interaction between toll-like receptor 4 polymorphism and abdominal obesity on ovarian cancer risk in Chinese women.

Zhu J et al.

Bmc Women's Health, 2025

TLR4 rs2149356 Polymorphism in Periodontitis and End-Stage Renal Disease: An Exploratory Analysis in Egyptian Patients.

Abou-Bakr A et al.

Cells, 2025

TLR-4 genetic variants as predictive biomarkers for susceptibility and clinical outcomes in triple-negative breast cancer: A case control study.

El-Ghali RM et al.

Gene, 2025

Correction: Role of TLR4 Asp299Gly and Thr399Ile Gene Polymorphisms as a Risk Factor in Human Cytomegalovirus Positive Pregnant Women.

Fatima T et al.

Reproductive Sciences (thousand Oaks, Calif.), 2025

Genetic Variations in TLR2 and TLR4 Genes and Their Association With COVID-19 Severity and Inflammatory Markers in the Moroccan Population.

Noureddine R et al.

International Journal of Immunogenetics, 2025

Impact of Sociodemographic, Clinical, and Genetic Factors and Fusobacterium nucleatum on Premature Birth Outcomes in Women from Kazakhstan: A Case-Control Study.

Zhurabekova G et al.

Iranian Journal of Medical Sciences, 2025

Genetic and immunological regulation of gut Microbiota: The Roles of TLRs, CLRs, and key proteins in microbial homeostasis and disease.

Ayoub M et al.

Gene, 2025

Role of TLR4 Asp299Gly and Thr399Ile Gene Polymorphisms as a Risk Factor in Human Cytomegalovirus Positive Pregnant Women.

Fatima T et al.

Reproductive Sciences (thousand Oaks, Calif.), 2025

TLR8 and TLR9 gene polymorphisms and the risk of high-grade serous ovarian cancer.

Haręża DA et al.

International Journal of Biological Macromolecules, 2025

Genetic Predisposition of TLR 1 and TLR 6 Polymorphisms to Schizophrenia Onset and Prediction of Treatment Response.

Aflouk Y et al.

Biochemical Genetics, 2025

Toll-like receptors polymorphisms and COVID-19: a systematic review.

Dos Santos BRC et al.

Molecular and Cellular Biochemistry, 2025

Host Genetic Factors in Q Fever Susceptibility.

Robaina Bordón JM et al.

Pathogens (basel, Switzerland), 2025

Metabolic Characteristics and Cytokine Gene Polymorphisms as Potential Risk Factors for a Higher Liver Fibrosis Stage in MASLD Patients: A Hospital-Based Study.

Iancu M et al.

International Journal of Molecular Sciences, 2025

Structural insights into ACE2 interactions and immune activation of SARS-CoV-2 and its variants: an in-silico study.

Yousefbeigi S et al.

Journal of Biomolecular Structure & Dynamics, 2025

TLR4 and TNF-α single nucleotide polymorphisms in patients with brucellosis: Association with infection complications.

Giannitsioti E et al.

European Journal of Internal Medicine, 2025

Associations between Toll-like receptor 4 Asp299Gly polymorphism and susceptibility to intracranial aneurysm among male and female patients within the North Indian population.

Singh A et al.

Neurological Research, 2025

Association of toll-like receptor 4 gene (Thr399Ile) polymorphism with type II diabetes mellitus patients.

Mohammed AJ et al.

Wiadomosci Lekarskie (warsaw, Poland : 1960), 2025

Identification of novel amino acid variants in the Han Chinese population that impair toll-like receptor 4 signaling and confer hyporesponsiveness to lipopolysaccharide.

Zhou B et al.

Frontiers in Immunology, 2025

TLR4 rs11536889 and rs1927914 SNPs are Associated with Ischemic Stroke Risk in a Southern Chinese Han Population.

Liu Y et al.

International Journal of General Medicine, 2025

Investigation of TLR4 Polymorphism in Children with Vesicoureteral Reflux and Renal Scarring.

Sav NM et al.

Balkan Journal of Medical Genetics : Bjmg, 2024

Single Nucleotide Polymorphisms on Toll-like Receptor-4 and the Risk of Developing Skin Cancer.

Yusuf N et al.

International Journal of Molecular Sciences, 2024

Association of TLR4 polymorphisms (Asp299Gly and Thr399Ile) with sepsis: a meta-analysis and trial sequence analysis.

Mu J et al.

Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, 2024

Allelic, Genotypic, and Haplotypic Analysis of Cytokine IL17A, IL17F, and Toll-like Receptor TLR4 Gene Polymorphisms in Metabolic-Dysfunction-Associated Steatotic Liver Disease: Insights from an Exploratory Study.

Coste SC et al.

Life (basel, Switzerland), 2024

TLR4 Polymorphisms (T399I/D299G) Association with Schizophrenia and Bipolar Disorder in a Tunisian Population.

Aflouk Y et al.

Biochemical Genetics, 2024

Validating genetic variants in innate immunity linked to infectious events in acute myeloid leukemia post-induction chemotherapy.

Schnetzke U et al.

Genes and Immunity, 2024

TLR2 and TLR4 Polymorphisms Are Not Associated with Dental Caries in Polish Children.

Milona M et al.

International Journal of Molecular Sciences, 2024

Pharmacokinetic and neuroimmune pharmacogenetic impacts on slow-release morphine cancer pain control and adverse effects.

Barratt DT et al.

The Pharmacogenomics Journal, 2024

38824169 (PubMed )
Supplement: 41397_2024_339_MOESM3_ESM.pdf

The relationship between the rs4986791 variant of the TLR4 gene and the severity of bronchial asthma in children.

Chen X et al.

Asian Pacific Journal of Allergy and Immunology, 2024

Genetics of ischemic stroke functional outcome.

Carnwath TP et al.

Journal of Neurology, 2024

Genetic variants associated with dengue hemorrhagic fever. A systematic review and meta-analysis.

Kanan M et al.

Journal of Infection and Public Health, 2024

Genetic Association of Toll-Like Receptor 4 (TLR4) Gene Polymorphism (rs4986790) With Oral Squamous Cell Carcinoma (OSCC): A Pilot Case-Control Study.

Gautam B et al.

Cureus, 2024

Impact of toll-like receptor 4 variations on nasopharyngeal carcinoma risk and survival in tunisian population.

Ben Chaaben A et al.

La Tunisie Medicale, 2024

Impact of genetic background as a risk factor for atherosclerotic cardiovascular disease: A protocol for a nationwide genetic case-control (CV-GENES) study in Brazil.

Alves de Oliveira H et al.

Plos One, 2024

38478535 (PubMed )
Supplement: pone.0289439.s002.pdf

Polymorphisms in Immune Genes and Their Association with Tuberculosis Susceptibility: An Analysis of the African Population.

Wodelo W et al.

The Application of Clinical Genetics, 2024

Altered levels of IFN-γ, IL-4, and IL-5 depend on the TLR4 rs4986790 genotype in COPD smokers but not those exposed to biomass-burning smoke.

Gutiérrez-Romero KJ et al.

Frontiers in Immunology, 2024

Restoring AIBP expression in the retina provides neuroprotection in glaucoma.

Ju WK et al.

Biorxiv : the Preprint Server for Biology, 2023

Single-nucleotide polymorphisms of TLR4 and GAS7 linked to primary open-angle glaucoma among patients of Shenyang, China.

Jie J et al.

Experimental Biology and Medicine (maywood, N.j.), 2023

No Association between SARS-CoV-2 Infection and the Polymorphism of the Toll-like Receptor 7 (TLR7) Gene in Female Population.

Zayed M et al.

Diagnostics (basel, Switzerland), 2023

Behçet's Disease: A Comprehensive Review on the Role of HLA-B*51, Antigen Presentation, and Inflammatory Cascade.

Khoshbakht S et al.

International Journal of Molecular Sciences, 2023

Frequency of toll-like receptor 4 variants and association with treatment response in children with primary immune thrombocytopenia.

Ahmed HA et al.

Pediatric Blood & Cancer, 2023

M2a macrophages facilitate resolution of chemically-induced colitis in TLR4-SNP mice.

Vlk AM et al.

Mbio, 2023

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."