Varaico: Literature-Extracted Genetic Variants

Gene:TLR5
Variant:p.F616L
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TLR5

NM_003268.6:p.F616L

Associated Papers

Pharmacogenomic landscape of TNF inhibitors in the Middle Eastern Qatari population.

Jan Z et al.

Frontiers in Immunology, 2025

41346622 (PubMed )
Supplement: Table2.xlsx › Supplementary_Table_8

Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.

Yang N et al.

Bmc Pediatrics, 2024

38310242 (PubMed )
Supplement: 12887_2024_4553_MOESM1_ESM.xlsx › trio.hg38.filter

Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms.

Pape K et al.

Cancers, 2022

36291768 (PubMed )
Supplement: cancers-14-04984-s001.zip › Table_S2.xlsx › DD204

TLR5 Variants Are Associated with the Risk for COPD and NSCLC Development, Better Overall Survival of the NSCLC Patients and Increased Chemosensitivity in the H1299 Cell Line.

Baranašić J et al.

Biomedicines, 2022

NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium.

Manuel Sánchez-Maldonado J et al.

Scientific Reports, 2020

Toll-like receptor polymorphism in host immune response to infectious diseases: A review.

Mukherjee S et al.

Scandinavian Journal of Immunology, 2019

Pattern recognition receptor polymorphisms in early periodontitis.

Leite FRM et al.

Journal of Periodontology, 2019

Polymorphism in Toll-Like Receptors and Helicobacter Pylori Motility in Autoimmune Atrophic Gastritis and Gastric Cancer.

De Re V et al.

Cancers, 2019

TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease.

Chakrabarty P et al.

The Journal of Experimental Medicine, 2018

TLR5 rs5744174 gene polymorphism is associated with the virus etiology of infant bronchiolitis but not with post-bronchiolitis asthma.

Törmänen S et al.

Health Science Reports, 2018

The association of variations in TLR genes and spontaneous immune control of hepatitis B virus.

Katrinli S et al.

Clinics and Research in Hepatology and Gastroenterology, 2018

Whole exome sequencing in three families segregating a pediatric case of sarcoidosis.

Calender A et al.

Bmc Medical Genomics, 2018

29510755 (PubMed )
Supplement: 12920_2018_338_MOESM6_ESM.xlsx › T2

TLR5 Polymorphisms rs2072493, rs5744174, and rs5744168 Are Not Genetic Risk Factors for Chronic Helicobacter pylori Infection in Indian Tamils.

Goda V et al.

Immunological Investigations, 2017

Evaluation of Toll-like-receptor gene family variants as prognostic biomarkers in rheumatoid arthritis.

Torices S et al.

Immunology Letters, 2017

Genetic variation of the Toll-like receptors in a Swedish allergic rhinitis case population.

Henmyr V et al.

Bmc Medical Genetics, 2017

28228119 (PubMed )
Supplement: 12881_2017_379_MOESM8_ESM.xlsx › TabS4

Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.

Maguire SL et al.

The Journal of Pathology, 2016

27512948 (PubMed )
Supplement: PATH-240-315-s015.xlsx › Table_S2

[THE ROLE OF GENETIC POLYMORPHISMS TOLL-LIKE RECEPTOR 4 AND 7 IN THE CHRONIC HEPATITIS C AND GENDER FEATURES OF THEIR DISTRIBUTION].

Sizovа L et al.

Georgian Medical News, 2016

Characterization of Disease-Associated Mutations in Human Transmembrane Proteins.

Molnár J et al.

Plos One, 2016

26986070 (PubMed )
Supplement: pone.0151760.s001.xlsx › polymorphism

Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2.

Visschedijk MC et al.

Plos One, 2016

27490946 (PubMed )
Supplement: pone.0159609.s002.xlsx › Results_Discovery_phase_I

Evaluation of Hybridization Capture Versus Amplicon-Based Methods for Whole-Exome Sequencing.

Samorodnitsky E et al.

Human Mutation, 2015

26110913 (PubMed )
Supplement: HUMU-36-903-s001.zip › humu22825-sup-00010-Table_S13.xlsx › Sheet1

Personal exposure to PM2.5, genetic variants and DNA damage: a multi-center population-based study in Chinese.

Chu M et al.

Toxicology Letters, 2015

The role of Toll-like receptor polymorphisms in acute pancreatitis occurrence and severity.

Matas-Cobos AM et al.

Pancreas, 2015

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes.

Prescott NJ et al.

Plos Genetics, 2015

25671699 (PubMed )
Supplement: pgen.1004955.s006.xlsx › SNVs

Toll-Like Receptor Family Polymorphisms Are Associated with Primary Renal Diseases but Not with Renal Outcomes Following Kidney Transplantation.

Dessing MC et al.

Plos One, 2015

The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.

Tang X et al.

Nucleic Acids Research, 2014

25352556 (PubMed )
Supplement: supp_gku1005_nar-01266-met-n-2014-File012.xlsx › TCGA-AO-A03R-01A.domain

Linking genetic variation in human Toll-like receptor 5 genes to the gut microbiome's potential to cause inflammation.

Leifer CA et al.

Immunology Letters, 2014

Screen of whole blood responses to flagellin identifies TLR5 variation associated with outcome in melioidosis.

Chantratita N et al.

Genes and Immunity, 2014

Functional TLR5 genetic variants affect human colorectal cancer survival.

Klimosch SN et al.

Cancer Research, 2013

Genetic variations in toll-like receptor pathway and lung function decline in Cystic fibrosis patients.

Haerynck F et al.

Human Immunology, 2013

A non-synonymous coding variant (L616F) in the TLR5 gene is potentially associated with Crohn's disease and influences responses to bacterial flagellin.

Sheridan J et al.

Plos One, 2013

Toll-like receptor and hepatitis B virus clearance in chronic infected patients: a long-term prospective cohort study in Taiwan.

Wu JF et al.

The Journal of Infectious Diseases, 2012

Host immune gene polymorphisms were associated with the prognosis of non-small-cell lung cancer in Chinese.

Dai J et al.

International Journal of Cancer, 2012

Identification of a potential susceptibility locus for macular telangiectasia type 2.

Parmalee NL et al.

Plos One, 2012

Association of toll-like receptor 5 gene polymorphism with susceptibility to ossification of the posterior longitudinal ligament of the spine in korean population.

Chung WS et al.

Journal of Korean Neurosurgical Society, 2011

Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome.

Coenen MJ et al.

Plos One, 2010

The heterogeneous allelic repertoire of human toll-like receptor (TLR) genes.

Georgel P et al.

Plos One, 2009

Multiple sclerosis and polymorphisms of innate pattern recognition receptors TLR1-10, NOD1-2, DDX58, and IFIH1.

Enevold C et al.

Journal of Neuroimmunology, 2009

Characterization and functional investigation of single nucleotide polymorphisms (SNPs) in the human TLR5 gene.

Merx S et al.

Human Mutation, 2006

Polymorphism report: identification of two common single nucleotide polymorphisms in the human toll-like receptor 5 (TLR5) gene.

Kao YL et al.

Molecular and Cellular Probes, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."