Varaico: Literature-Extracted Genetic Variants

Gene:TLR7
Variant:p.Q11L
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TLR7

NM_016562.4:p.Q11L

Associated Papers

Host genetic factors modulating dengue virus: a systematic review of TLR polymorphisms.

Candrasari DS et al.

Bmc Infectious Diseases, 2026

Juvenile-onset Systemic Lupus Erythematosus: Recent Advances in Pathogenesis and Treatment.

Natoli V et al.

Current Rheumatology Reports, 2025

Common Toll-like receptor 7 variants define disease risk and phenotypes in juvenile-onset systemic lupus erythematosus.

Renaudineau Y et al.

Journal of Autoimmunity, 2025

Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation.

Cieri N et al.

Nature Biotechnology, 2025

From Rare to Common: Genetic Insights into TLR7 Variants in a Multicentric Spanish Study on COVID-19 Severity.

Antolí A et al.

Journal of Clinical Immunology, 2025

An integrated approach to predict genetic risk for Mosquito-Borne diseases in the local Population of Tehsil Haripur, Khyber Pakhtunkhwa, Pakistan.

Basri R et al.

Scientific Reports, 2025

39875533 (PubMed )
Supplement: 41598_2025_88095_MOESM2_ESM.docx

Pharmacogenomics and genetic ancestry in Colombia: a study on all variant drug annotations of PharmGKB.

Acosta-Monterrosa AA et al.

Frontiers in Pharmacology, 2025

40949159 (PubMed )
Supplement: Table1.xlsx › Studies

Systematic assessment of COVID-19 host genetics using whole genome sequencing data.

Schmidt A et al.

Plos Pathogens, 2024

39715278 (PubMed )
Supplement: ppat.1012786.s013.xlsx › Tabelle1

TLR7 rs179008 (A/T) and TLR7 rs3853839 (C/G) polymorphisms are associated with variations in IFN-α levels in HTLV-1 infection.

Santana EGM et al.

Frontiers in Immunology, 2024

TLRs: Innate Immune Sentries against SARS-CoV-2 Infection.

Mantovani S et al.

International Journal of Molecular Sciences, 2023

Impact of host genetic polymorphisms on response to inactivated influenza vaccine in children.

Tsang TK et al.

Npj Vaccines, 2023

Meta-analysis of the association between toll-like receptor gene polymorphisms and hepatitis C virus infection.

Du Y et al.

Frontiers in Microbiology, 2023

Gain-of-function TLR7 and loss-of-function A20 gene variants identify a novel pathway for Mendelian lupus and lupus nephritis.

Villalvazo P et al.

Clinical Kidney Journal, 2022

Host genomics of SARS-CoV-2 infection.

Redin C et al.

European Journal of Human Genetics : Ejhg, 2022

Methylene-tetrahydrofolate reductase gene C677T and A1298C polymorphisms as a risk factor for Crimean-Congo hemorrhagic fever.

Karakus N et al.

Nucleosides, Nucleotides & Nucleic Acids, 2022

Genetic variants determine intrafamilial variability of SARS-CoV-2 clinical outcomes in 19 Italian families.

Azzarà A et al.

Plos One, 2022

Synonymous and non-synonymous polymorphisms in toll-like receptor 2 (TLR2) gene among complicated measles cases at a tertiary care hospital, Peshawar, Pakistan.

Ilyas M et al.

Saudi Medical Journal, 2021

Case report: hepatitis in a child infected with SARS-CoV-2 presenting toll-like receptor 7 Gln11Leu single nucleotide polymorphism.

Pessoa NL et al.

Virology Journal, 2021

Impact of TLR7 and TLR9 polymorphisms on susceptibility to placental infections and pregnancy complications.

Sánchez-Luquez K et al.

Journal of Reproductive Immunology, 2021

Differential genotypic signatures of Toll-like receptor polymorphisms among dengue-chikungunya mono- and co-infected Eastern Indian patients.

Sengupta S et al.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 2021

Single Nucleotide Polymorphisms in Genes Encoding Toll-Like Receptors 7 and 8 and Their Association with Proviral Load of SRLVs in Goats of Polish Carpathian Breed.

Olech M et al.

Animals : an Open Access Journal From Mdpi, 2021

Escape from X Chromosome Inactivation and the Female Predominance in Autoimmune Diseases.

Youness A et al.

International Journal of Molecular Sciences, 2021

Type I Interferon and the Spectrum of Susceptibility to Viral Infection and Autoimmune Disease: A Shared Genomic Signature.

Sugrue JA et al.

Frontiers in Immunology, 2021

Association of toll-like receptor polymorphisms with acquisition of HIV infection and clinical findings: A protocol for systematic review and meta-analysis.

Shi H et al.

Medicine, 2020

Association of Genetic Polymorphisms in TLR3, TLR4, TLR7, and TLR8 with the Clinical Forms of Dengue in Patients from Veracruz, Mexico.

Posadas-Mondragón A et al.

Viruses, 2020

Interleukin-6 -174 G/C polymorphism is associated with the risk of basal cell carcinoma in a Chinese Han population.

Wang J et al.

Aging, 2020

Distinct and Orchestrated Functions of RNA Sensors in Innate Immunity.

Liu G et al.

Immunity, 2020

TLR7 dosage polymorphism shapes interferogenesis and HIV-1 acute viremia in women.

Azar P et al.

Jci Insight, 2020

Genetic variation in toll like receptors 2, 7, 9 and interleukin-6 is associated with cytomegalovirus infection in late pregnancy.

Mhandire DZ et al.

Bmc Medical Genetics, 2020

TLR7 Polymorphism (rs179008 and rs179009) in HIV-Infected Individual Naïve to ART.

Singh H et al.

Mediators of Inflammation, 2020

Effects of TLR7 Polymorphisms on the Susceptibility and Progression of HIV-1 Infection in Chinese MSM Population.

Zhang T et al.

Frontiers in Immunology, 2020

Toll-like receptor polymorphism in host immune response to infectious diseases: A review.

Mukherjee S et al.

Scandinavian Journal of Immunology, 2019

Polymorphisms in Toll-Like Receptors (TLRs)-7 and 9 Genes in Indian Population with Progressive and Nonprogressive HIV-1 Infection.

Shaikh N et al.

Aids Research and Human Retroviruses, 2019

The association of single nucleotide polymorphisms of Toll-like receptor 3, Toll-like receptor 7 and Toll-like receptor 8 genes with the susceptibility to HCV infection.

El-Bendary M et al.

British Journal of Biomedical Science, 2018

TLR7 polymorphism, sex and chronic HBV infection influence plasmacytoid DC maturation by TLR7 ligands.

Buschow SI et al.

Antiviral Research, 2018

Genetic variations in toll-like receptors 7 and 8 modulate natural hepatitis C outcomes and liver disease progression.

Fakhir FZ et al.

Liver International : Official Journal of the International Association for the Study of the Liver, 2018

Genetically defined variants of toll-like receptors 3, 7 and 9 as phenotype and risk modifier factors for psoriasis.

Julià M et al.

Journal of Dermatological Science, 2018

TLR7 escapes X chromosome inactivation in immune cells.

Souyris M et al.

Science Immunology, 2018

Association of toll-like receptor polymorphisms with susceptibility to chikungunya virus infection.

Dutta SK et al.

Virology, 2017

Toll like receptor7 polymorphisms in relation to disease susceptibility and progression in Chinese patients with chronic HBV infection.

Zhu J et al.

Scientific Reports, 2017

Evaluation of Toll-like-receptor gene family variants as prognostic biomarkers in rheumatoid arthritis.

Torices S et al.

Immunology Letters, 2017

Viral and host factors associated with outcomes of hepatitis C virus infection (Review).

Yan Z et al.

Molecular Medicine Reports, 2017

Polymorphisms of Mannose-binding Lectin and Toll-like Receptors 2, 3, 4, 7 and 8 and the Risk of Respiratory Infections and Acute Otitis Media in Children.

Toivonen L et al.

The Pediatric Infectious Disease Journal, 2017

Genetic variation of the Toll-like receptors in a Swedish allergic rhinitis case population.

Henmyr V et al.

Bmc Medical Genetics, 2017

28228119 (PubMed )
Supplement: 12881_2017_379_MOESM8_ESM.xlsx › TabS4

Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children.

Studzińska M et al.

Plos One, 2017

Rapidity of fibrosis progression in liver transplant recipients with recurrent hepatitis C is influenced by toll-like receptor 3 polymorphism.

Citores MJ et al.

Clinical Transplantation, 2016

TLR7 Gln11Leu single nucleotide polymorphism and susceptibility to cutaneous melanoma.

Elefanti L et al.

Oncology Letters, 2016

TLR7 rs2897827 Polymorphism Affects TLR7 Gene mRNA Expression and Serum Apolipoprotein A1 Level of Ischemic Stroke Patients in a Chinese Han Population.

Gu L et al.

Journal of Molecular Neuroscience : Mn, 2016

Toll-Like Receptors 2 and 4 Polymorphisms in Age-Related Macular Degeneration.

Güven M et al.

Current Eye Research, 2016

Association between Toll-like receptor 7 Gln11Leu single-nucleotide polymorphism and basal cell carcinoma.

Russo I et al.

Biomedical Reports, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."