Varaico: Literature-Extracted Genetic Variants

Gene:TLR7
Variant:p.V219I
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TLR7

NM_016562.4:p.V219I

Associated Papers

From Rare to Common: Genetic Insights into TLR7 Variants in a Multicentric Spanish Study on COVID-19 Severity.

Antolí A et al.

Journal of Clinical Immunology, 2025

The role of TLR7 agonists in modulating COVID-19 severity in subjects with loss-of-function TLR7 variants.

Naushad SM et al.

Scientific Reports, 2023

TLRs: Innate Immune Sentries against SARS-CoV-2 Infection.

Mantovani S et al.

International Journal of Molecular Sciences, 2023

Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients.

Mantovani S et al.

Genes and Immunity, 2022

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.

Asano T et al.

Science Immunology, 2021

Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study.

Fallerini C et al.

Elife, 2021

Genetic variation of the Toll-like receptors in a Swedish allergic rhinitis case population.

Henmyr V et al.

Bmc Medical Genetics, 2017

28228119 (PubMed )
Supplement: 12881_2017_379_MOESM8_ESM.xlsx › TabS4
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."