Associated Papers
From Rare to Common: Genetic Insights into TLR7 Variants in a Multicentric Spanish Study on COVID-19 Severity.
Antolí A et al.
Journal of Clinical Immunology, 2025
Stratified analyses refine association between TLR7 rare variants and severe COVID-19.
Boos J et al.
Hgg Advances, 2024
The role of TLR7 agonists in modulating COVID-19 severity in subjects with loss-of-function TLR7 variants.
Naushad SM et al.
Scientific Reports, 2023
TLRs: Innate Immune Sentries against SARS-CoV-2 Infection.
Mantovani S et al.
International Journal of Molecular Sciences, 2023
Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients.
Mantovani S et al.
Genes and Immunity, 2022
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.
Asano T et al.
Science Immunology, 2021
Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study.
Fallerini C et al.
Elife, 2021
Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19.
Solanich X et al.
Frontiers in Immunology, 2021
Association of toll-like receptor polymorphisms with acquisition of HIV infection and clinical findings: A protocol for systematic review and meta-analysis.
Shi H et al.
Medicine, 2020
Evaluation of Toll-like-receptor gene family variants as prognostic biomarkers in rheumatoid arthritis.
Torices S et al.
Immunology Letters, 2017
Genetic variation of the Toll-like receptors in a Swedish allergic rhinitis case population.
Henmyr V et al.
Bmc Medical Genetics, 2017
Genotypic distribution of common variants of endosomal toll like receptors in healthy Spanish women. A comparative study with other populations.
Martínez-Robles E et al.
Gene, 2016
Molecular Determinants of GS-9620-Dependent TLR7 Activation.
Rebbapragada I et al.
Plos One, 2016
RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events.
Colak E et al.
Journal of Immunology (baltimore, Md. : 1950), 2014
A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators.
Broen JC et al.
Arthritis and Rheumatism, 2012
Multiplex screening of 22 single-nucleotide polymorphisms in 7 Toll-like receptors: an association study in rheumatoid arthritis.
Enevold C et al.
The Journal of Rheumatology, 2010
The heterogeneous allelic repertoire of human toll-like receptor (TLR) genes.
Georgel P et al.
Plos One, 2009
Multiple sclerosis and polymorphisms of innate pattern recognition receptors TLR1-10, NOD1-2, DDX58, and IFIH1.
Enevold C et al.
Journal of Neuroimmunology, 2009
A frequent functional toll-like receptor 7 polymorphism is associated with accelerated HIV-1 disease progression.
Oh DY et al.
Aids (london, England), 2009
Polymorphisms in Toll-like receptor 9 influence the clinical course of HIV-1 infection.
Bochud PY et al.
Aids (london, England), 2007