Varaico: Literature-Extracted Genetic Variants

Gene:TLR7
Variant:p.V795F
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TLR7

NM_016562.4:p.V795F

Associated Papers

Identification of a novel TLR7 gain-of-function variant that underlies systemic lupus erythematosus.

Sethumadhavan A et al.

Journal of Human Immunity, 2026

Toll-like Receptors in Inborn Errors of Immunity in Children: Diagnostic Potential and Therapeutic Frontiers-A Review of the Latest Data.

Jurczuk A et al.

Cells, 2025

From Rare to Common: Genetic Insights into TLR7 Variants in a Multicentric Spanish Study on COVID-19 Severity.

Antolí A et al.

Journal of Clinical Immunology, 2025

Innate immune responses to RNA: sensing and signaling.

Luan X et al.

Frontiers in Immunology, 2024

The role of TLR7 agonists in modulating COVID-19 severity in subjects with loss-of-function TLR7 variants.

Naushad SM et al.

Scientific Reports, 2023

TLRs: Innate Immune Sentries against SARS-CoV-2 Infection.

Mantovani S et al.

International Journal of Molecular Sciences, 2023

Novel TLR7 hemizygous variant in post-COVID-19 neurological deterioration: a case report with literature review.

Noor Eddin A et al.

Frontiers in Neurology, 2023

An overview of human proteins and genes involved in SARS-CoV-2 infection.

Jahanafrooz Z et al.

Gene, 2022

Human genetic basis of coronavirus disease 2019.

Deng H et al.

Signal Transduction and Targeted Therapy, 2021

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.

Asano T et al.

Science Immunology, 2021

Hypotheses and facts for genetic factors related to severe COVID-19.

Kotsev SV et al.

World Journal of Virology, 2021

COVID-19: The Effect of Host Genetic Variations on Host-Virus Interactions.

Chakravarty S

Journal of Proteome Research, 2021

Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19.

Solanich X et al.

Frontiers in Immunology, 2021

Presence of Genetic Variants Among Young Men With Severe COVID-19.

van der Made CI et al.

Jama, 2020

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